Highly robust hydrogels via a fast, simple and cytocompatible dual crosslinking-based process

被引：32

作者：

Costa, Ana M. S. ^{[1
]}

Mano, Joao F. ^{[1
]}

机构：

[1] Univ Minho, Headquarters European Inst Excellence Tissue Engn, Res Grp Biomat Biodegradables & Biomimet 3Bs, P-4805017 Barcogmr, Portugal

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 86期

关键词：

DOUBLE-NETWORK HYDROGELS; HIGH MECHANICAL STRENGTH; TOUGH; HYSTERESIS; RECOVERY; BEHAVIOR; STRAIN;

D O I：

10.1039/c5cc05564d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly robust hydrogel device made from a single biopolymer formulation is reported. Owing to the presence of covalent and non-covalent crosslinks, these engineered systems were able to (i) sustain a compressive strength of ca. 20 MPa, (ii) quickly recover upon unloading, and (iii) encapsulate cells with high viability rates.

引用

页码：15673 / 15676

页数：4

共 25 条

[1] Recovery from applied strain in interpenetrating polymer network hydrogels with ionic and covalent cross-links [J].

Bakarich, Shannon E. ;

Pidcock, Geoffrey C. ;

Balding, Paul ;

Stevens, Leo ;

Calvert, Paul ;

Panhuis, Marc In Het .

SOFT MATTER, 2012, 8 (39) :9985-9988

[2] A Robust, One-Pot Synthesis of Highly Mechanical and Recoverable Double Network Hydrogels Using Thermoreversible Sol-Gel Polysaccharide [J].

Chen, Qiang ;

Zhu, Lin ;

Zhao, Chao ;

Wang, Qiuming ;

Zheng, Jie .

ADVANCED MATERIALS, 2013, 25 (30) :4171-4176

[3] Double network hydrogel with high mechanical strength: Performance, progress and future perspective [J].

Chen YongMei ;

Dong Kun ;

Liu ZhenQi ;

Xu Feng .

SCIENCE CHINA-TECHNOLOGICAL SCIENCES, 2012, 55 (08) :2241-2254

[4] Extremely strong and tough hydrogels as prospective candidates for tissue repair - A review [J].

Costa, Ana M. S. ;

Mano, Joao F. .

EUROPEAN POLYMER JOURNAL, 2015, 72 :344-364

[5] Why are double network hydrogels so tough? [J].

Gong, Jian Ping .

SOFT MATTER, 2010, 6 (12) :2583-2590

[6] Double-network hydrogels with extremely high mechanical strength [J].

Gong, JP ;

Katsuyama, Y ;

Kurokawa, T ;

Osada, Y .

ADVANCED MATERIALS, 2003, 15 (14) :1155-+

[7] Lamellar Bilayers as Reversible Sacrificial Bonds To Toughen Hydrogel: Hysteresis, Self-Recovery, Fatigue Resistance, and Crack Blunting [J].

Haque, M. Anamul ;

Kurokawa, Takayuki ;

Kamita, Gen ;

Gong, J. Ping .

MACROMOLECULES, 2011, 44 (22) :8916-8924

[8] Mechanically strong hydrogels with reversible behaviour under cyclic compression with MPa loading [J].

Harrass, Konstantina ;

Krueger, Reinhard ;

Moeller, Martin ;

Albrecht, Krystyna ;

Groll, Juergen .

SOFT MATTER, 2013, 9 (10) :2869-2877

[9] The compressive strength of articular cartilage [J].

Kerin, AJ ;

Wisnom, MR ;

Adams, MA .

PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, 1998, 212 (H4) :273-280

[10] Robust biopolymer based ionic-covalent entanglement hydrogels with reversible mechanical behaviour [J].

Kirchmajer, Damian M. ;

Panhuis, Marc In Het .

JOURNAL OF MATERIALS CHEMISTRY B, 2014, 2 (29) :4694-4702

← 1 2 3 →