Prolonged respiratory viral shedding in transplant patients

被引：46

作者：

de Lima, C. R. A. ^{[1
]}

Mirandolli, T. B. ^{[1
]}

Carneiro, L. C. ^{[1
]}

Tusset, C. ^{[1
]}

Romer, C. M. ^{[1
]}

Andreolla, H. F. ^{[2
]}

Baethgen, L. F. ^{[1
]}

Pasqualotto, A. C. ^{[1
,2
]}

机构：

[1] UFCSPA, Dept Basic Hlth Sci, Porto Alegre, RS, Brazil

[2] Santa Casa de Misericordia Porto Alegre, Mol Biol Lab, BR-90035074 Porto Alegre, RS, Brazil

来源：

TRANSPLANT INFECTIOUS DISEASE | 2014年 / 16卷 / 01期

关键词：

respiratory tract infection; viruses; PCR; transplant infectious diseases; STEM-CELL TRANSPLANTATION; VIRUS-INFECTIONS; SOLID-ORGAN; IMMUNOFLUORESCENCE; RECIPIENTS; BOCAVIRUS; OUTBREAK; CHILDREN;

D O I：

10.1111/tid.12167

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Respiratory viral infections are frequent causes of morbidity in transplant patients. We screened symptomatic adult transplant recipients for respiratory viruses in a cohort of patients attending a referral medical center in Brazil. The duration of viral shedding and the prevalence of viral codetections were also determined. During a 1-year period (2011-2012), swabs were obtained from 50 patients. An in-house polymerase chain reaction panel designed to detect 10 viruses was used. Viruses were identified in 19 (38%) patients, particularly parainfluenza III (32%) and the respiratory syncytial virus (20%); multiple viruses were identified in 26% of patients. Prolonged viral shedding was observed with 60% of individuals excreting viruses for >10days. The clinical and epidemiologic relevance of prolonged viral shedding remains to be determined.

引用

页码：165 / 169

页数：5

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