Antioxidant and cytotoxic activities of Caesalpinia pulcherrima wood

被引:0
|
作者
Pawar, C. R. [1 ]
Mutha, R. E. [1 ]
Landge, A. D. [2 ]
Jadhav, R. B. [1 ]
Surana, S. J. [1 ]
机构
[1] RC Patel Coll Pharm, Dept Pharmacognosy, Dhule 425405, MS, India
[2] Amrutvahini Coll Pharm, Ahmednagar, MS, India
来源
INDIAN JOURNAL OF BIOCHEMISTRY & BIOPHYSICS | 2009年 / 46卷 / 02期
关键词
Caesalpinia pulcherrima; Antioxidant activity; Cytotoxic activity; Total phenolic content; BRINE SHRIMP;
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Antioxidant and cytotoxic activities of the methanolic and aqueous extracts of Caesalpinia pulcherrima wood were studied in in vitro models. Both extracts exhibited strong antioxidant activity, as evidenced by the low IC50 values in both 1,1-diphenyl-2-picryl hydrazyl (DPPH), nitric oxide and superoxide scavenging methods; the values were found to be less or comparable to those of gallic acid, the standard used. To determine the cytotoxic activity, extracts were tested for toxic effects to brine shrimp larvae. In this assay, the methanolic extract had little effect, but aqueous extract was relatively toxic. The antioxidant and cytotoxic activities may be attributed to the total phenolic content in the wood.
引用
收藏
页码:198 / 200
页数:3
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