Viral Pneumonia in Patients with H ematologic Malignancy or H ematopoietic Stem Cell Transplantation

被引:22
作者
Vakil, Erik [1 ]
Evans, Scott E. [2 ]
机构
[1] Univ Texas Hlth Sci Ctr, Dept Pulm Crit Care & Sleep Med, Div Internal Med, 6431 Fannin St,MSB 1-434, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Pulm Med, Div Internal Med, 1515 Holcombe Blvd,Unit 1100, Houston, TX 77030 USA
关键词
Viral pneumonia; Hematologic malignancy; Stem cell transplant; Immunocompromised host pneumonia; RESPIRATORY SYNCYTIAL VIRUS; HUMAN METAPNEUMOVIRUS INFECTION; POLYMERASE-CHAIN-REACTION; BONE-MARROW-TRANSPLANTATION; RESOLUTION CT FINDINGS; VERSUS-HOST-DISEASE; PARAINFLUENZA VIRUS; CYTOMEGALOVIRUS-INFECTION; RISK-FACTORS; BRONCHOALVEOLAR LAVAGE;
D O I
10.1016/j.ccm.2016.11.002
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
Viral pneumonias in patients with hematologic malignancies and recipients of hematopoietic stem cell transplantation cause significant morbidity and mortality. Advances in diagnostic techniques have enabled rapid identification of respiratory viral pathogens from upper and lower respiratory tract samples. Lymphopenia, myeloablative and T -cell depleting chemotherapy, graft-versus-host disease, and other factors increase the risk of developing life-threatening viral pneumonia. Chest imaging is often nonspecific but may aid in diagnoses. Bronchoscopy with bronchoalveolar lavage is recommended in those at high risk for viral pneumonia who have new infiltrates on chest imaging.
引用
收藏
页码:97 / +
页数:16
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