Recent Evidence Regarding Triclosan and Cancer Risk

被引:64
作者
Dinwiddie, Michael T. [1 ]
Terry, Paul D. [1 ,2 ]
Chen, Jiangang [1 ]
机构
[1] Univ Tennessee, Dept Publ Hlth, Knoxville, TN 37996 USA
[2] Univ Tennessee, Dept Surg, Med Ctr, Knoxville, TN 37920 USA
来源
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH | 2014年 / 11卷 / 02期
关键词
triclosan; epidemiologic studies; breast neoplasms; cancer; xenoestrogens; fatty acid synthesis; FATTY-ACID SYNTHASE; BREAST-CANCER; IN-VITRO; BLOOD-SERUM; BISPHENOL-A; HUMAN-MILK; EXPOSURE; CELLS; ESTROGEN; XENOESTROGENS;
D O I
10.3390/ijerph110202209
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Triclosan is a broad-spectrum antibacterial commonly used in cosmetics, dentifrices, and other consumer products. The compound's widespread use in consumer products and its detection in breast milk, urine, and serum have raised concerns regarding its potential association with various human health outcomes. Recent evidence suggests that triclosan may play a role in cancer development, perhaps through its estrogenicity or ability to inhibit fatty acid synthesis. Our aims here are to review studies of human exposure levels, to evaluate the results of studies examining the effects of triclosan on cancer development, and to suggest possible directions for future research.
引用
收藏
页码:2209 / 2217
页数:9
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