Gene expression of peroxisomal β-oxidation enzymes in rat brain

被引：9

作者：

Knoll, A

Sargueil, F

Salles, J

Cassagne, C

Garbay, B

机构：

[1] Univ Bordeaux 2, Lab Biogenese Membranaire, CNRS, UMR 5544, F-33076 Bordeaux, France

[2] Univ Bordeaux 2, ESTBB, F-33076 Bordeaux, France

来源：

MOLECULAR BRAIN RESEARCH | 1999年 / 74卷 / 1-2期

关键词：

brain; very-long-chain fatty acids; peroxisomes; beta-oxidation; development; myelination;

D O I：

10.1016/S0169-328X(99)00252-1

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Despite increasing insight into peroxisomal beta-oxidation, it is still not clear which enzymes catalyze very-long-chain fatty acid degradation. Using the northern blot and RT-PCR techniques, a brain-specific expression is demonstrated for acyl-CoA oxidase 3II mRNA, thiolase-A and trans2,3enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase multifunctional enzyme type 2. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：217 / 220

页数：4

共 19 条

[1] Substrate specificities of 3-oxoacyl-CoA thiolase A and sterol carrier protein 2/3-oxoacyl-CoA thiolase purified from normal rat liver peroxisomes - Sterol carrier protein 2/3-oxoacyl-CoA thiolase is involved in the metabolism of 2-methyl-branched fatty acids and bile acid intermediates [J].