In France there is no official recommendation for the drug management of nausea and vomiting during pregnancy. In the USA, Canada and Australia, vitamin B6 is officially recommended in the treatment of mild to moderate pregnancy sickness and vomiting. Indeed, some studies have shown some effectiveness of oral vitamin B6, most often in combination with doxylamine, in comparison with a placebo. In addition, the harmlessness of oral vitamin B6 during pregnancy has been established for doses up to 40-60 mg/day, mainly in combination with doxylamine (40 mg/40 mg). Thus, in France, as in other countries, vitamin B6 could be integrated into the therapeutic arsenal of mild to moderate nausea and vomiting during pregnancy according to the following dosage schedule: oral intake of 10 mg four times a day of a compounded preparation of vitamin B6, alone or in combination with doxylamine. (C) 2020 Elsevier Masson SAS. All rights reserved.
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Zunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R ChinaZunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R China
He, Ling
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Zunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R ChinaZunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R China
Fan, Yulin
Hu, Yuanmei
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Zunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R ChinaZunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R China
Hu, Yuanmei
Tian, Chunhua
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Zunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R ChinaZunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R China
Tian, Chunhua
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Zunyi Med Univ, Lab Morphol, Zunyi, Peoples R ChinaZunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R China
Tian, Ying
Zhang, Jidong
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Zunyi Med Univ, Dept Immunol, Zunyi 563000, Guizhou, Peoples R China
Zunyi Med Univ, Special Key Lab Gene Detect & Therapy Guizhou Prov, Zunyi, Peoples R ChinaZunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R China
Zhang, Jidong
Ren, Yanping
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Zunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R ChinaZunyi Med Univ, Dept Histol & Embryol, Zunyi 563000, Guizhou, Peoples R China
Ren, Yanping
Tan, Jun
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