Utility of 16S ribosomal DNA sequencing in the diagnosis of Staphylococcus lugdunensis native valve infective endocarditis: case report and literature review

被引：7

作者：

Pada, Surinder ^{[1
]}

Lye, David C. ^{[1
]}

Leo, Yee Sin ^{[1
]}

Barkham, Timothy ^{[2
]}

机构：

[1] Tan Tock Seng Hosp, Dept Infect Dis, Singapore 308433, Singapore

[2] Tan Tock Seng Hosp, Dept Lab Med, Tan Tock Seng, Singapore

来源：

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES | 2009年 / 13卷 / 06期

关键词：

Culture-negative infective endocarditis; Molecular diagnosis; Coagulase-negative Staphylococcus; CULTURE-NEGATIVE ENDOCARDITIS; ETIOLOGIC DIAGNOSIS; PCR AMPLIFICATION;

D O I：

10.1016/j.ijid.2009.02.019

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We report a case of possible infective endocarditis without fever presenting with an acutely ischemic limb with prior antimicrobial therapy preventing identification by culture of a microorganism. 16S ribosomal DNA sequencing led to the identification of Staphylococcus lugdunensis from an embolus removed at surgery and subsequent successful antibiotic treatment. We review the utility of 16S ribosomal DNA sequencing in diagnosing infective endocarditis and other infectious conditions. (C) 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

引用

页码：E511 / E513

页数：3

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