TFAA-Catalyzed Annulation Synthesis of Spiro Pyrrolo[1,2-a]quinoxaline Derivatives from 1-(2-Aminophenyl)pyrroles and Benzoquinones/Ketones

被引：18

作者：

Ni, Jixiang ^{[1
]}

Jiang, Yong ^{[2
]}

Qi, Zhenjie ^{[1
]}

Yan, Rulong ^{[1
]}

机构：

[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China

[2] Yangtze Normal Univ, Sch Chem & Chem Engn, Chongqing, Peoples R China

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2019年 / 14卷 / 16期

基金：

中国国家自然科学基金;

关键词：

benzoquinones; cyclic ketones; pyrroles; spiro pyrrolo[1,2-a]quinoxalines; trifluorosulfonate anhydride; ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; BRONSTED ACID; EFFICIENT; IMINOQUINONE; CLEAVAGE; KETONES;

D O I：

10.1002/asia.201900567

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A metal-free trifluorosulfonate anhydride (TFAA)-catalyzed strategy for the synthesis of spiro pyrrolo[1,2-a]quinoxalines from 1-(2-aminophenyl)pyrroles and benzoquinones/ketones has been developed. With this general method, spiro pyrrolo[1,2-a]quinoxalines have been accessed via nucleophilic addition and cyclization. This reaction exhibits good functional group tolerance, and a wide range of products are obtained in moderate to good yields.

引用

页码：2898 / 2902

页数：5

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