TFAA-Catalyzed Annulation Synthesis of Spiro Pyrrolo[1,2-a]quinoxaline Derivatives from 1-(2-Aminophenyl)pyrroles and Benzoquinones/Ketones

被引：18
|
作者：
Ni, Jixiang [1 ]
Jiang, Yong [2 ]
Qi, Zhenjie [1 ]
Yan, Rulong [1 ]
机构：
[1] Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China
[2] Yangtze Normal Univ, Sch Chem & Chem Engn, Chongqing, Peoples R China
来源：
CHEMISTRY-AN ASIAN JOURNAL | 2019年 / 14卷 / 16期
基金：
中国国家自然科学基金;
关键词：
benzoquinones; cyclic ketones; pyrroles; spiro pyrrolo[1,2-a]quinoxalines; trifluorosulfonate anhydride; ONE-POT SYNTHESIS; BIOLOGICAL EVALUATION; BRONSTED ACID; EFFICIENT; IMINOQUINONE; CLEAVAGE; KETONES;
D O I：
10.1002/asia.201900567
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A metal-free trifluorosulfonate anhydride (TFAA)-catalyzed strategy for the synthesis of spiro pyrrolo[1,2-a]quinoxalines from 1-(2-aminophenyl)pyrroles and benzoquinones/ketones has been developed. With this general method, spiro pyrrolo[1,2-a]quinoxalines have been accessed via nucleophilic addition and cyclization. This reaction exhibits good functional group tolerance, and a wide range of products are obtained in moderate to good yields.
引用
收藏
页码：2898 / 2902
页数：5
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