Prostatic Ductal Adenocarcinoma: A Mini Review

被引：45
作者：
Epstein, Jonathan I. [1 ,2 ,3 ]
机构：
[1] Johns Hopkins Univ Hosp, Dept Pathol, Baltimore, MD 21287 USA
[2] Johns Hopkins Univ Hosp, Dept Urol, Baltimore, MD 21287 USA
[3] Johns Hopkins Univ Hosp, Dept Oncol, Baltimore, MD 21287 USA
来源：
MEDICAL PRINCIPLES AND PRACTICE | 2010年 / 19卷 / 01期
关键词：
Prostate adenocarcinoma; Ductal adenocarcinoma; Gleason grade; ENDOMETRIOID FEATURES; RADICAL PROSTATECTOMY; CARCINOMA; IMMUNOHISTOCHEMISTRY; PATHOLOGY; BIOPSY;
D O I：
10.1159/000252842
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Prostatic ductal adenocarcinomas may arise either in large primary periurethral prostatic ducts or in the peripheral prostatic ducts. Ductal adenocarcinomas are composed of tall columnar cells arranged in cribriform, papillary, solid, single glands, and PIN-like patterns. Other than the prostatic intraepithelial neoplasia (PIN)-like ductal pattern, which behaves like Gleason pattern 3, ductal adenocarcinoma is comparable to Gleason pattern 4 prostate cancer. Ductal adenocarcinoma can have a patchy basal cell layer and typically expresses prostate-specific antigen (PSA) immunohistochemically. Mimickers of ductal adenocarcinoma include prostatic urethral polyps, hyperplastic benign prostate glands, high-grade PIN, colorectal adenocarcinoma, and papillary urothelial carcinoma. Copyright (C) 2009 S. Karger AG, Basel
引用
收藏
页码：82 / 85
页数：4
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