Border-cell migration: The race is on

被引:250
作者
Montell, DJ [1 ]
机构
[1] Johns Hopkins Sch Med, Dept Biol Chem, Baltimore, MD 21205 USA
关键词
D O I
10.1038/nrm1006
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The conversion of stationary epithelial cells into migratory, invasive cells is important for normal embryonic development and tumour metastasis. Border-cell migration in the ovary of Drosophila melanogaster has emerged as a simple, genetically tractable model for studying this process. Three distinct signals, which are also upregulated in cancer, control border-cell migration, so identifying further genes that are involved in border-cell migration could provide new insights into tumour invasion.
引用
收藏
页码:13 / 24
页数:12
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