A novel RNA-binding motif in influenza A virus non-structural protein 1

被引：94

作者：

Chien, CY

Tejero, R

Huang, YP

Zimmerman, DE

Rios, CB

Krug, RM

Montelione, GT

机构：

[1] RUTGERS STATE UNIV,CTR ADV BIOTECHNOL & MED,PISCATAWAY,NJ 08854

[2] RUTGERS STATE UNIV,DEPT MOL BIOL & BIOCHEM,PISCATAWAY,NJ 08854

[3] UNIV VALENCIA,DEPT QUIM FIS,E-46100 BURJASSOT,VALENCIA,SPAIN

来源：

NATURE STRUCTURAL BIOLOGY | 1997年 / 4卷 / 11期

关键词：

D O I：

10.1038/nsb1197-891

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The solution NMR structure of the RNA-binding domain from influenza virus non-structural protein 1 exhibits a novel dimeric six-helical protein fold, Distributions of basic residues and conserved salt bridges of dimeric NS1(1-73) suggest that the face containing antiparallel helices 2 and 2' forms a novel arginine-rich nucleic acid binding motif.

引用

收藏

页码：891 / 895

页数：5

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