A role for oncostatin M in inflammatory bowel disease

被引：23
作者：
Kim, Walter M. [1 ]
Kaser, Arthur [2 ]
Blumberg, Richard S. [1 ]
机构：
[1] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Gastroenterol, Boston, MA 02115 USA
[2] Univ Cambridge, Dept Med, Div Gastroenterol & Hepatol, Cambridge, England
来源：
NATURE MEDICINE | 2017年 / 23卷 / 05期
关键词：
MAINTENANCE THERAPY; ULCERATIVE-COLITIS; CROHNS-DISEASE; INDUCTION; VEDOLIZUMAB;
D O I：
10.1038/nm.4338
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A new study identifies oncostatin M (OSM) as a potential biomarker and therapeutic target for anti-tumor necrosis factor (TNF)-refractory inflammatory bowel disease (IBD), and pinpoints mucosal stromal cells as key players in OSM-mediated inflammation.
引用
收藏
页码：535 / 536
页数：2
相关论文
共 50 条
  • [31] The Role of Autophagy in Inflammatory Bowel Disease
    Shao, Bo-Zong
    Yao, Yi
    Zhai, Jun-Shan
    Zhu, Jian-Hua
    Li, Jin-Ping
    Wu, Kai
    FRONTIERS IN PHYSIOLOGY, 2021, 12
  • [32] Role of cytokines in inflammatory bowel disease
    Sanchez-Munoz, Fausto
    Dominguez-Lopez, Aaron
    Yamamoto-Furusho, Jesus K.
    WORLD JOURNAL OF GASTROENTEROLOGY, 2008, 14 (27) : 4280 - 4288
  • [33] The role of probiotics in inflammatory bowel disease
    Jones, Jennifer L.
    Foxx-Orenstein, Amy E.
    DIGESTIVE DISEASES AND SCIENCES, 2007, 52 (03) : 607 - 611
  • [34] Role of angiogenesis in inflammatory bowel disease
    Koutroubakis, Ioannis E.
    Tsiolakidou, Georgia
    Karmiris, Konstantinos
    Kouroumalis, Elias A.
    INFLAMMATORY BOWEL DISEASES, 2006, 12 (06) : 515 - 523
  • [35] Role of cytokines in inflammatory bowel disease
    Fausto Sanchez-Muoz
    Aaron Dominguez-Lopez
    Jesus K Yamamoto-Furusho
    World Journal of Gastroenterology, 2008, (27) : 4280 - 4288
  • [36] Role of scintigraphy in inflammatory bowel disease
    Stathaki, Maria I.
    Koukouraki, Sophia I.
    Karkavitsas, Nikolaos S.
    Koutroubakis, Ioannis E.
    WORLD JOURNAL OF GASTROENTEROLOGY, 2009, 15 (22) : 2693 - 2700
  • [37] Role of endoscopy in inflammatory bowel disease
    Bharadwaj, Shishira
    Narula, Neeraj
    Tandon, Parul
    Yaghoobi, Mohammad
    GASTROENTEROLOGY REPORT, 2018, 6 (02): : 75 - 82
  • [38] Role of scintigraphy in inflammatory bowel disease
    Maria I Stathaki
    Sophia I Koukouraki
    Nikolaos S Karkavitsas
    Ioannis E Koutroubakis
    World Journal of Gastroenterology, 2009, 15 (22) : 2693 - 2700
  • [39] Role of MiRNAs in Inflammatory Bowel Disease
    Cao, Bo
    Zhou, Xin
    Ma, Jiaojiao
    Zhou, Wei
    Yang, Wanli
    Fan, Daiming
    Hong, Liu
    DIGESTIVE DISEASES AND SCIENCES, 2017, 62 (06) : 1426 - 1438
  • [40] Role of probiotics in inflammatory bowel disease
    Darmadi, Darmadi
    Ariestine, Dina Aprillia
    Surja, Sem Samuel
    RAWAL MEDICAL JOURNAL, 2023, 48 (02): : 537 - 541
12345