Emergence of carbapenem-resistant ST131 Escherichia coli carrying blaOXA-244 in Germany, 2019 to 2020

被引：18
作者：
Welker, Sybille [1 ]
Boutin, Sebastien [2 ]
Miethke, Thomas [1 ]
Heeg, Klaus [2 ]
Nurjadi, Dennis [2 ]
机构：
[1] Heidelberg Univ, Med Fac Mannheim, Inst Med Microbiol & Hyg, Mannheim, Germany
[2] Heidelberg Univ Hosp, Dept Infect Dis, Med Microbiol & Hyg, Heidelberg, Germany
来源：
EUROSURVEILLANCE | 2020年 / 25卷 / 46期
基金：
英国科研创新办公室;
关键词：
ANTIMICROBIAL RESISTANCE; OXA-244;
D O I：
10.2807/1560-7917.ES.2020.25.46.2001815
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.
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页数：8
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共 28 条
  • [11] Hoyos-Mallecot Y, 2017, ANTIMICROB AGENTS CH, V61, DOI [10.1128/AAC.00818-17, 10.1128/aac.00818-17]
  • [12] CARD 2017: expansion and model-centric curation of the comprehensive antibiotic resistance database
    Jia, Baofeng
    Raphenya, Amogelang R.
    Alcock, Brian
    Waglechner, Nicholas
    Guo, Peiyao
    Tsang, Kara K.
    Lago, Briony A.
    Dave, Biren M.
    Pereira, Sheldon
    Sharma, Arjun N.
    Doshi, Sachin
    Courtot, Melanie
    Lo, Raymond
    Williams, Laura E.
    Frye, Jonathan G.
    Elsayegh, Tariq
    Sardar, Daim
    Westman, Erin L.
    Pawlowski, Andrew C.
    Johnson, Timothy A.
    Brinkman, Fiona S. L.
    Wright, Gerard D.
    McArthur, Andrew G.
    [J]. NUCLEIC ACIDS RESEARCH, 2017, 45 (D1) : D566 - D573
  • [13] Comparative genomic analysis reveals a high prevalence of inter-species in vivo transfer of carbapenem-resistance plasmids in patients with haematological malignancies
    Kocer, K.
    Boutin, S.
    Dalpke, A. H.
    Heeg, K.
    Mutters, N. T.
    Nurjadi, D.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2020, 26 (06) : 780.e1 - 780.e8
  • [14] Rapid spread of OXA-244-producing Escherichia coli ST38 in Germany: insights from an integrated molecular surveillance approach; 2017 to January 2020
    Kremer, Katrin
    Kramer, Rolf
    Neumann, Bernd
    Haller, Sebastian
    Pfennigwerth, Niels
    Werner, Guido
    Gatermann, Soeren
    Schroten, Horst
    Eckmanns, Tim
    Hans, Joerg B.
    [J]. EUROSURVEILLANCE, 2020, 25 (25):
  • [15] Ongoing dissemination of OXA-244 carbapenemase-producing Escherichia coli in Switzerland and their detection
    Masseron, Amandine
    Poirel, Laurent
    Falgenhauer, Linda
    Imirzalioglu, Can
    Kessler, Julie
    Chakraborty, Trinad
    Nordmann, Patrice
    [J]. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2020, 97 (03)
  • [16] Antimicrobial susceptibility testing of colistin - evaluation of seven commercial MIC products against standard broth microdilution for Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter spp.
    Matuschek, E.
    Ahman, J.
    Webster, C.
    Kahlmeter, G.
    [J]. CLINICAL MICROBIOLOGY AND INFECTION, 2018, 24 (08) : 865 - 870
  • [17] Virulence Patterns in a Murine Sepsis Model of ST131 Escherichia coli Clinical Isolates Belonging to Serotypes O25b:H4 and O16:H5 Are Associated to Specific Virotypes
    Mora, Azucena
    Dahbi, Ghizlane
    Lopez, Cecilia
    Mamani, Rosalia
    Marzoa, Juan
    Dion, Sara
    Picard, Bertrand
    Blanco, Miguel
    Pilar Alonso, Maria
    Denamur, Erick
    Blanco, Jorge
    [J]. PLOS ONE, 2014, 9 (01):
  • [18] Escherichia coli ST131, an Intriguing Clonal Group
    Nicolas-Chanoine, Marie-Helene
    Bertrand, Xavier
    Madec, Jean-Yves
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 2014, 27 (03) : 543 - 574
  • [19] Emergence of OXA-48-producing Klebsiella pneumoniae and the novel carbapenemases OXA-244 and OXA-245 in Spain
    Oteo, Jesus
    Manuel Hernandez, Juan
    Espasa, Mateu
    Fleites, Ana
    Saez, David
    Bautista, Veronica
    Perez-Vazquez, Maria
    Dolores Fernandez-Garcia, Ma
    Delgado-Iribarren, Alberto
    Sanchez-Romero, Isabel
    Garcia-Picazo, Luisa
    Dolores Miguel, Ma
    Solis, Sonia
    Aznar, Esteban
    Trujillo, Gloria
    Mediavilla, Concepcion
    Fontanals, Dionisia
    Rojo, Susana
    Vindel, Ana
    Campos, Jose
    [J]. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2013, 68 (02) : 317 - 321
  • [20] Roary: rapid large-scale prokaryote pan genome analysis
    Page, Andrew J.
    Cummins, Carla A.
    Hunt, Martin
    Wong, Vanessa K.
    Reuter, Sandra
    Holden, Matthew T. G.
    Fookes, Maria
    Falush, Daniel
    Keane, Jacqueline A.
    Parkhill, Julian
    [J]. BIOINFORMATICS, 2015, 31 (22) : 3691 - 3693
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