Emergence of carbapenem-resistant ST131 Escherichia coli carrying blaOXA-244 in Germany, 2019 to 2020

被引：18
作者：
Welker, Sybille [1 ]
Boutin, Sebastien [2 ]
Miethke, Thomas [1 ]
Heeg, Klaus [2 ]
Nurjadi, Dennis [2 ]
机构：
[1] Heidelberg Univ, Med Fac Mannheim, Inst Med Microbiol & Hyg, Mannheim, Germany
[2] Heidelberg Univ Hosp, Dept Infect Dis, Med Microbiol & Hyg, Heidelberg, Germany
来源：
EUROSURVEILLANCE | 2020年 / 25卷 / 46期
基金：
英国科研创新办公室;
关键词：
ANTIMICROBIAL RESISTANCE; OXA-244;
D O I：
10.2807/1560-7917.ES.2020.25.46.2001815
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 Escherichia coli in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing E. coli may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 E. coli is of clinical relevance and should be monitored closely.
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