Lyapunov functions for tuberculosis models with fast and slow progression

被引:91
作者
McCluskey, C. Connell [1 ]
机构
[1] Wilfrid Laurier Univ, Dept Math, Waterloo, ON N2L 3C5, Canada
关键词
Lyapunov function; global stability; tuberculosis; fast and slow progression;
D O I
10.3934/mbe.2006.3.603
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
The spread of tuberculosis is studied through two models which include fast and slow progression to the infected class. For each model, Lyapunov functions are used to show that when the basic reproduction number is less than or equal to one, the disease-free equilibrium is globally asymptotically stable, and when it is greater than one there is an endemic equilibrium which is globally asymptotically stable.
引用
收藏
页码:603 / 614
页数:12
相关论文
共 8 条
[1]   THE INTRINSIC TRANSMISSION DYNAMICS OF TUBERCULOSIS EPIDEMICS [J].
BLOWER, SM ;
MCLEAN, AR ;
PORCO, TC ;
SMALL, PM ;
HOPEWELL, PC ;
SANCHEZ, MA ;
MOSS, AR .
NATURE MEDICINE, 1995, 1 (08) :815-821
[2]   Dynamical models of tuberculosis and their applications [J].
Castillo-Chavez, C ;
Song, BJ .
MATHEMATICAL BIOSCIENCES AND ENGINEERING, 2004, 1 (02) :361-404
[3]  
Goh B.S., 1980, MANAGEMENT ANAL BIOL
[4]  
Korobeinikov A, 2004, MATH BIOSCI ENG, V1, P57
[5]  
Korobeinikov A, 2004, MATH MED BIOL, V21, P75
[6]  
LaSalle J.P., 1976, Society For Industrial and Applied Mathematics
[7]  
Takeuchi Y., 1996, GLOBAL DYNAMICAL PRO
[8]   Reproduction numbers and sub-threshold endemic equilibria for compartmental models of disease transmission [J].
van den Driessche, P ;
Watmough, J .
MATHEMATICAL BIOSCIENCES, 2002, 180 :29-48