Immune therapy of metastatic melanoma developing after allogeneic bone marrow transplant

被引：8

作者：

Cecchini, Michael ^{[1
]}

Sznol, Mario ^{[1
]}

Seropian, Stuart ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Div Med Oncol, Yale Canc Ctr,Smilow Canc Hosp,Yale New Haven Hos, New Haven, CT 06504 USA

来源：

JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2015年 / 3卷

关键词：

Melanoma; Immunotherapy; Interleukin-2; Graft vs host disease; Allogeneic transplant; Ipilimumab; CTLA-4; antigen; Programmed cell death 1 receptor and immune-related adverse events; BLOCKADE; MALIGNANCY; RELAPSE;

D O I：

10.1186/s40425-015-0054-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Metastatic melanoma is frequently treated with immune activating therapy, which poses a theoretical risk of inducing graft versus host disease (GVHD) in those who have received allogeneic stem cell transplantation. The literature reporting the safety of immunotherapy in post transplant patients is limited. We report two patients with metastatic melanoma who received treatment with immunotherapy after allogeneic stem cell transplantation that did not result in GVHD.

引用

页数：4

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