Executive summary: Japanese guidelines for atopic dermatitis (ADGL) 2021

被引：52

作者：

Saeki, Hidehisa ^{[1
]}

Ohya, Yukihiro ^{[2
]}

Furuta, Junichi ^{[3
]}

Arakawa, Hirokazu ^{[4
]}

Ichiyama, Susumu ^{[1
]}

Katsunuma, Toshio ^{[5
]}

Katoh, Norito ^{[6
]}

Tanaka, Akio ^{[7
]}

Tsunemi, Yuichiro ^{[8
]}

Nakahara, Takeshi ^{[9
]}

Nagao, Mizuho ^{[10
]}

Narita, Masami ^{[11
]}

Hide, Michihiro ^{[12
]}

Fujisawa, Takao ^{[10
]}

Futamura, Masaki ^{[13
]}

Masuda, Koji ^{[6
]}

Matsubara, Tomoyo ^{[14
]}

Murota, Hiroyuki ^{[15
]}

Yamamoto-Hanada, Kiwako ^{[2
]}

机构：

[1] Nippon Med Sch, Dept Dermatol, 1-1-5 Sendagi,Bunkyo Ku, Tokyo 1138603, Japan

[2] Natl Ctr Child Hlth & Dev, Allergy Ctr, Tokyo, Japan

[3] Univ Tsukuba, Med Informat & Management, Fac Med, Tsukuba, Ibaraki, Japan

[4] Kibounoie Hosp, Kitakanto Allergy Res Inst, Gunma, Japan

[5] Jikei Univ, Daisan Hosp, Dept Pediat, Tokyo, Japan

[6] Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Dermatol, Kyoto, Japan

[7] Hiroshima Univ, Grad Sch Biomed & Hlth Sci, Dept Dermatol, Hiroshima, Japan

[8] Saitama Med Univ, Dept Dermatol, Saitama, Japan

[9] Kyushu Univ, Grad Sch Med Sci, Dept Dermatol, Fukuoka, Japan

[10] Natl Hosp Org Mie Natl Hosp, Allergy Ctr, Tsu, Mie, Japan

[11] Kyorin Univ, Dept Pediat, Fac Med, Tokyo, Japan

[12] Hiroshima Citizens Hosp, Dept Dermatol, Hiroshima, Japan

[13] Natl Hosp Org Nagoya Med Ctr, Div Pediat, Nagoya, Aichi, Japan

[14] Dokkyo Med Univ, Saitama Med Ctr, Dept Pediat, Saitama, Japan

[15] Nagasaki Univ, Grad Sch Biomed Sci, Dept Dermatol, Nagasaki, Japan

来源：

ALLERGOLOGY INTERNATIONAL | 2022年 / 71卷 / 04期

关键词：

Atopic dermatitis; Clinical practice guidelines; Clinical questions; Evidence-based medicine; Treatment; JANUS KINASE INHIBITOR; TOPICAL CORTICOSTEROIDS; AUREUS COLONIZATION; ADULT PATIENTS; CHILDREN; ECZEMA; MANAGEMENT; SEVERITY; MODERATE; SAFETY;

D O I：

10.1016/j.alit.2022.06.009

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

This is an abridged edition of English version of the Clinical Practice Guidelines for the Management of Atopic Dermatitis 2021. Atopic dermatitis (AD) is a disease characterized by relapsing eczema with pruritus as a primary lesion. In Japan, from the perspective of evidence-based medicine, the current strategies for the treatment of AD consist of three primary measures: (i) use of topical corticosteroids, tacrolimus ointment, and delgocitinib ointment as the main treatment of the inflammation; (ii) topical application of emollients to treat the cutaneous barrier dysfunction; and (iii) avoidance of apparent exacerbating factors, psychological counseling, and advice about daily life. In the present revised guidelines, the description about three new drugs, namely, dupilumab, delgocitinib, and baricitinib, has been added. The guidelines present recommendations to review clinical research articles, evaluate the balance between the advantages and disadvantages of medical activities, and optimize medical activity-related patient outcomes with respect to several important points requiring decision-making in clinical practice. Copyright (c) 2022, Japanese Society of Allergology. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

引用

页码：448 / 458

页数：11

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