Molecular cloning and characterization of a cDNA encoding a transferrin homolog from Bombyx mori

被引：41

作者：

Yun, EY

Kang, SW

Hwang, JS

Goo, TW

Kim, SH

Jin, BR

Kwon, OY

Kim, KY ^{[1
]}

机构：

[1] Natl Inst Agr Sci & Technol, Dept Sericulture & Entomol, RDA, Suwon 441100, South Korea

[2] Dong A Univ, Coll Nat Resources & Life Sci, Pusan 604714, South Korea

[3] Chungnam Natl Univ, Coll Med, Taejon 301131, South Korea

来源：

BIOLOGICAL CHEMISTRY | 1999年 / 380卷 / 12期

关键词：

Bombyx mori; E-coli; transferrin;

D O I：

10.1515/BC.1999.188

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We isolated a cDNA representing a message that was strongly induced by injection with E. coli in Bombyx mori. The 2160 bp cDNA has an open reading frame of 644 amino acids and the deduced product a predicted molecular mass of 71 kDa. The cDNA sequence shared high homology with the transferrins known so far, and its deduced peptide had unique features of transferrins, that is, sites of cystein residues and iron binding. We suggest that the B. mori transferrin plays an important role in the self-defense system.

引用

收藏

页码：1455 / 1459

页数：5

相关论文

共 21 条

[1] STRUCTURE OF HUMAN LACTOFERRIN - CRYSTALLOGRAPHIC STRUCTURE-ANALYSIS AND REFINEMENT AT 2.8-A RESOLUTION [J].

ANDERSON, BF ;

BAKER, HM ;

NORRIS, GE ;

RICE, DW ;

BAKER, EN .

JOURNAL OF MOLECULAR BIOLOGY, 1989, 209 (04) :711-734

[2] MOLECULAR-STRUCTURE OF SERUM TRANSFERRIN AT 3.3-A RESOLUTION [J].

BAILEY, S ;

EVANS, RW ;

GARRATT, RC ;

GORINSKY, B ;

HASNAIN, S ;

HORSBURGH, C ;

JHOTI, H ;

LINDLEY, PF ;

MYDIN, A ;

SARRA, R ;

WATSON, JL .

BIOCHEMISTRY, 1988, 27 (15) :5804-5812

[3] NUCLEOTIDE-SEQUENCE OF PORCINE LIVER TRANSFERRIN [J].

BALDWIN, GS ;

WEINSTOCK, J .

NUCLEIC ACIDS RESEARCH, 1988, 16 (17) :8720-8720

[4] THE NUCLEOTIDE-SEQUENCE OF RABBIT LIVER TRANSFERRIN CDNA [J].

BANFIELD, DK ;

CHOW, BKC ;

FUNK, WD ;

ROBERTSON, KA ;

UMELAS, TM ;

WOODWORTH, RC ;

MACGILLIVRAY, RTA .

BIOCHIMICA ET BIOPHYSICA ACTA, 1991, 1089 (02) :262-265

[5]

BARTFELD NS, 1990, J BIOL CHEM, V265, P21684

[6] THE SEQUENCE 5'-AAUAAA-3' FORMS PART OF THE RECOGNITION SITE FOR POLYADENYLATION OF LATE SV40 MESSENGER-RNAS [J].

FITZGERALD, M ;

SHENK, T .

CELL, 1981, 24 (01) :251-260

[7] IRON-BINDING PROTEINS AND THEIR ROLES IN THE TOBACCO HORNWORM, MANDUCA-SEXTA (L) [J].

HUEBERS, HA ;

HUEBERS, E ;

FINCH, CA ;

WEBB, BA ;

TRUMAN, JW ;

RIDDIFORD, LM ;

MARTIN, AW ;

MASSOVER, WH .

JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY, 1988, 158 (03) :291-300

[8] TRANSFERRIN IN A COCKROACH - MOLECULAR-CLONING, CHARACTERIZATION, AND SUPPRESSION BY JUVENILE-HORMONE [J].

JAMROZ, RC ;

GASDASKA, JR ;

BRADFIELD, JY ;

LAW, JH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (04) :1320-1324

[9] THE COMPLETE NUCLEOTIDE-SEQUENCE OF THE CHICKEN OVOTRANSFERRIN MESSENGER-RNA [J].

JELTSCH, JM ;

CHAMBON, P .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1982, 122 (02) :291-295

[10] Cloning and expression of a novel gene encoding a new antibacterial peptide from silkworm, Bombyx mori [J].

Kim, SH ;

Park, BS ;

Yun, FY ;

Je, YH ;

Woo, SD ;

Kang, SW ;

Kim, KY ;

Kang, SK .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1998, 246 (02) :388-392