A Scalable Rhodium-Catalyzed Intermolecular Aziridination Reaction

被引：12

作者：

Smith, David T. ^{[1
]}

Njardarson, Jon T. ^{[1
]}

机构：

[1] Univ Arizona, Dept Chem & Biochem, Tucson, AZ 85721 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2014年 / 53卷 / 17期

关键词：

aziridines; aziridination; heterocycles; nitrene; rhodium; ASYMMETRIC AZIRIDINATION; ORGANIC-SYNTHESIS; OLEFINS; AMINATION; ENONES; ACIDS;

D O I：

10.1002/anie.201400502

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The amine has landed! By employing the rhodium catalyst [Rh 2(esp)2] in the presence of a readily available amine source (DPH), unactivated and styrene-type olefins can now be stereospecifally transformed, in high yields at room temperature, into valuable NH aziridine products. esp=α,α,α?,α?-tetramethyl-1,3- benzenedipropionic acid. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：4278 / 4280

页数：3

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