Repeated TALEs Visualizing DNA sequence localization and chromosome dynamics in live cells

被引：5

作者：

Pederson, Thoru ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Dept Biochem & Mol Pharmacol, Program Cell & Dev Dynam, Worcester, MA 01605 USA

来源：

NUCLEUS | 2014年 / 5卷 / 01期

基金：

美国国家科学基金会;

关键词：

transcription activator-like effectors; telomeres; centromeres; single nucleotide polymorphisms; cell cycle; DNA replication timing; EFFECTORS; PROTEINS;

D O I：

10.4161/nucl.28143

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Three recent papers, published just weeks apart, describe the use of fluorescent TALEs to tag specific DNA sequences in live cells and, in one case, also in fixed cells, the latter with potential clinical applications.

引用

页码：28 / 31

页数：4

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