Evaluation of Subfoveal Choroidal Thickness in Pregnant Women Using Enhanced Depth Imaging Optical Coherence Tomography

Purpose: To evaluate the subfoveal choroidal thickness (SFCT) measured by enhanced depth imaging optical coherence tomography (EDI-OCT) in pregnant women. Methods: In this prospective and cross-sectional study, 100 pregnant women and 100 age-matched nonpregnant women were enrolled. The SFCT was measured by EDI-OCT. The refractive error, intraocular pressure (IOP), axial length (AL), central corneal thickness (CCT), systolic and diastolic blood pressure, and ocular perfusion pressure (OPP) were also measured. Pregnancy-related factors including gestational age, maternal weight gain, and fetal weight were noted. Results: Mean SFCT was 371.1 +/- 61.8 mm in the study group and 337.2 +/- 62.4 mu m in the control group (p<0.001). No significant correlation was found between SFCT and spherical refraction, IOP, AL, CCT, OPP, gestational age, maternal weight gain, or fetal weight. Conclusion: Our results suggest that subfoveal choroidal thickness increases in pregnant women compared with age-matched nonpregnant women.