Do preoperative leukocyte and neutrophil levels have a predictive value on the complications of hypospadias repair in children?

被引:2
作者
Akgul, Ahsen Karagozlu [1 ,6 ]
Abidoglu, Sadik [1 ,6 ]
Bakir, Ayten Ceren [2 ,7 ]
Adali, Embiye [3 ,8 ]
Kiyan, Gursu [4 ,7 ]
Tugtupe, Halil [5 ,9 ]
机构
[1] Marmara Univ, Dept Pediat Surg, Div Pediat Urol, Fac Med, Istanbul, Turkey
[2] Marmara Univ, Pendik Educ & Res Hosp, Dept Pediat Surg, Minist Hlth, Istanbul, Turkey
[3] St Helens & Knowsley Teaching Hosp, Dept Pediat Accid & Emergency Med, Liverpool, England
[4] Marmara Univ, Dept Pediat Surg, Fac Med, Istanbul, Turkey
[5] Tugtepe Ctr Pediat Urol & Pediat Surg, Istanbul, Turkey
[6] Marmara Univ, Pendik Educ & Res Hosp, Dept Pediat Surg, Div Pediat Urol, Muhsin Yazicioglu Cd 10, TR-34899 Istanbul, Turkey
[7] Muhsin Yazicioglu Cd 10, TR-34899 Istanbul, Turkey
[8] Apartment 503,West Africa House,25 Water St, Liverpool L2 0RG, England
[9] Senlik Sokagi 14-A, TR-34750 Istanbul, Turkey
关键词
Hypospadias; Leukocyte; Neutrophil; NLR; Complication; LYMPHOCYTE RATIO; TRANSURETHRAL RESECTION; STRICTURE RECURRENCE; URETHRAL STRICTURE; PROGNOSTIC-FACTOR; URETHROPLASTY; PLATELET;
D O I
10.4081/aiua.2022.4.459
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Objective: Surgeons observed that the out-comes after the same repair technique in the same type of hypospadias performed by the same surgeon may be different. There may be some indeterminate factors that influence the results such as subclinical inflammation. Our study evaluated the predictor values of inflammatory hematologic parameters on the complications after hypospadias repair. Materials and methods: We retrospectively reviewed the data of patients who underwent hypospadias repair between January 2016 and January 2019 in our clinic. Age at surgery, hypospa-dias type, repair technique, complications were recorded. Patients who underwent Snodgrass repair by a single surgeon were included in the study while patients who underwent differ-ent techniques or procedures that were performed by other sur-geons were excluded. The levels of white blood cell, neutrophil, lymphocyte, platelet and monocyte, the mean platelet volumes were recorded from blood test that were performed one day before surgery. Neutrophil-lymphocyte ratio (NLR), platelet -lymphocyte ratio (PLR), and other parameters were analyzed to determine their relationship with complications after hypospa-dias surgery. Results: WBC and neutrophil levels were statistically higher in patients with complications (p = 0.006 and 0.017 respectively). Other hematological parameters were not different between patients with or without complications. To predict the complica-tions, the WBC cutoff was 9500/mm(3), the neutrophil cutoff was 3000/mm(3). Conclusions: WBC and neutrophil values were statistically significant in predicting the complications after Snodgrass repair in patients with hypospadias. Our result determined no relation between complications and NLR, PLR.
引用
收藏
页码:459 / 463
页数:5
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