Osteoporosis in Inflammatory Arthritides: New Perspective on Pathogenesis and Treatment

被引：22
作者：
Rotta, Denise [1 ]
Fassio, Angelo [1 ]
Rossini, Maurizio [1 ]
Giollo, Alessandro [1 ]
Viapiana, Ombretta [1 ]
Orsolini, Giovanni [1 ]
Bertoldo, Eugenia [1 ]
Gatti, Davide [1 ]
Adami, Giovanni [1 ]
机构：
[1] Univ Verona, Rheumatol Unit, Verona, Italy
来源：
FRONTIERS IN MEDICINE | 2020年 / 7卷
关键词：
osteoporosis; rheumatoid arthritis; psoriatic arthritis; spondyloarthritis; fractures; bone mineral density; BONE-MINERAL DENSITY; CITRULLINATED PROTEIN ANTIBODIES; MODIFYING ANTIRHEUMATIC DRUGS; WNT SIGNALING ANTAGONISTS; RHEUMATOID-ARTHRITIS; ANKYLOSING-SPONDYLITIS; DOUBLE-BLIND; POSTMENOPAUSAL WOMEN; PSORIATIC-ARTHRITIS; VERTEBRAL FRACTURES;
D O I：
10.3389/fmed.2020.613720
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Osteoporosis is a skeletal disorder characterized by impaired bone strength and increased risk of fragility fracture and is among the most relevant comorbidities of rheumatic diseases. The purpose of the present review is to discuss the pathogenesis of local and systemic bone involvement in inflammatory arthritides, especially Rheumatoid Arthritis, Psoriatic Arthritis, and Spondyloarthritides, as well as the effect of anti-rheumatic treatments and anti-osteoporotic medication on bone health and fracture incidence, including recent data on novel therapeutic perspective.
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页数：10
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