Manoyloxide Sesterterpenoids from Salvia mirzayanii

被引:28
作者
Ebrahimi, Samad N. [1 ,2 ]
Farimani, M. Moridi [1 ]
Mirzania, Foroogh [1 ]
Soltanipoor, Mohammad A. [3 ]
De Mieri, Maria [2 ]
Hamburger, Matthias [2 ]
机构
[1] Shahid Beheshti Univ, Med Plants & Drugs Res Inst, Dept Phytochem, GC, Tehran, Iran
[2] Univ Basel, Dept Pharmaceut Sci, CH-4056 Basel, Switzerland
[3] Hormozgan Agr & Nat Resources Res Ctr, Bandarabbas, Iran
来源
JOURNAL OF NATURAL PRODUCTS | 2014年 / 77卷 / 04期
基金
瑞士国家科学基金会;
关键词
ABSOLUTE-CONFIGURATIONS; ABIETANE DITERPENOIDS; CONSTITUENTS; ANTIBACTERIAL; TERPENOIDS; SAHENDICA;
D O I
10.1021/np400948n
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Five new manoyloxide-type sesterterpenes were isolated from aerial parts of Salvia mirzayanii, a species endemic to Iran. The planar structures were established by means of ID and 2D NMR and HRESIMS. Compounds 1-3 differed only in their configurations at C-13 and C-14. Assignment of relative and absolute configurations was achieved by NOESY experiments and by comparison of experimental and simulated ECD spectra of possible stereoisomers. The absolute configurations of 4 and 5 were established in a similar manner.
引用
收藏
页码:848 / 854
页数:7
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