Association between Child Cortisol Levels in Saliva and Neuropsychological Development during the Second Year of Life

被引:10
作者
Forns, Joan [1 ,2 ,3 ]
Vegas, Oscar [4 ,5 ]
Julvez, Jordi [1 ,2 ,3 ,6 ]
Garcia-Esteban, Raquel [1 ,2 ,3 ]
Rivera, Marcela [1 ,2 ,3 ]
Lertxundi, Nerea [4 ,5 ]
Guxens, Monica [1 ,2 ,3 ]
Fano, Eduardo [4 ,5 ]
Ferrer, Muriel [1 ,2 ,3 ]
Grellier, James [1 ,2 ,3 ,7 ]
Ibarluzea, Jesus [5 ]
Sunyer, Jordi [1 ,2 ,3 ,8 ]
机构
[1] Ctr Res Environm Epidemiol CREAL, Barcelona 08003, Spain
[2] Hosp del Mar, Res Inst IMIM, Barcelona, Spain
[3] CIBER Epidemiol & Salud Publ CIBERESP, Barcelona, Spain
[4] Univ Basque Country, Fac Psychol, San Sebastian, Spain
[5] Basque Govt, Dept Hlth, Subdirecc Salud Publ Gipuzkoa, San Sebastian, Spain
[6] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA
[7] Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol & Biostat, London, England
[8] Pompeu Fabra Univ, Barcelona, Spain
关键词
cortisol; child development; social environment; neuropsychology; BREAST-FED INFANTS; BRAIN MATURATION; SEX-DIFFERENCES; STRESS; COGNITION; CORTICOSTEROIDS; TEMPERAMENT; REACTIVITY; GLUCOCORTICOIDS; POPULATION;
D O I
10.1002/smi.2504
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Exposure to highly elevated levels of cortisol has been linked with impairments in cognitive capacities in both children and adults. By contrast, moderate levels of cortisol may engender beneficial effects. The main aim of this study was to assess the association between child cortisol levels and neuropsychological development during the second year of life. A population-based birth cohort was established in the city of Sabadell (Catalonia, Spain) as part of the INMA (Environment and Childhood) Project. We assessed the cognitive and psychomotor development at the age of 14 months using the Bayley Scales of Infant Development (BSID). We included 302 children assessed during their second year of life for whom we had information on neuropsychological assessment and measurements of cortisol in saliva. Higher levels of cortisol were associated with better scores in BSID's mental scale. There was no association between cortisol levels and psychomotor test scores. We found a small positive association between duration of breastfeeding and child cortisol levels. This association was only found in boys. The results of this study suggest that moderate levels of cortisol in children could have small beneficial effects on their early neuropsychological development. Copyright (C) 2013 John Wiley & Sons, Ltd.
引用
收藏
页码:142 / 148
页数:7
相关论文
共 44 条
  • [1] Gender and its contribution to the prediction of cognitive abilities at 5 years
    Andersson, HW
    Sonnander, K
    Sommerfelt, K
    [J]. SCANDINAVIAN JOURNAL OF PSYCHOLOGY, 1998, 39 (04) : 267 - 274
  • [2] Bayley N., 1977, BAYLEY SCALES INFANT
  • [3] Breastfeeding modulates neonatal innate immune responses: a prospective birth cohort study
    Belderbos, M. E.
    Houben, M. L.
    van Bleek, G. M.
    Schuijff, L.
    van Uden, N. O. P.
    Bloemen-Carlier, E. M.
    Kimpen, J. L. L.
    Eijkemans, M. J. C.
    Rovers, M.
    Bont, L. J.
    [J]. PEDIATRIC ALLERGY AND IMMUNOLOGY, 2012, 23 (01) : 65 - 74
  • [4] Cognitive and behavioral outcomes of school-aged children who were born preterm - A meta-analysis
    Bhutta, AT
    Cleves, MA
    Casey, PH
    Cradock, MM
    Anand, KJS
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 288 (06): : 728 - 737
  • [5] Cortisol reactivity is positively related to executive function in preschool children attending head start
    Blair, C
    Granger, D
    Razza, RP
    [J]. CHILD DEVELOPMENT, 2005, 76 (03) : 554 - 567
  • [6] BURKE PM, 1985, AM J PSYCHIAT, V142, P1065
  • [7] Are Breast-fed Infants More Resilient? Feeding Method and Cortisol in Infants
    Cao, Yang
    Rao, Sanmati D.
    Phillips, Terry M.
    Umbach, David M.
    Bernbaum, Judy C.
    Archer, Janet I.
    Rogan, Walter J.
    [J]. JOURNAL OF PEDIATRICS, 2009, 154 (03) : 452 - 454
  • [8] Cattell R., 1977, ESCALAS 2 3
  • [9] Condon J. T., 1998, Journal of Reproductive and Infant Psychology, V16, P57, DOI [DOI 10.1080/02646839808404558, 10.1016/0022-3999(86)90044-9]
  • [10] The anterior attention network: Associations with temperament and neuroendocrine activity in 6-year-old children
    Davis, EP
    Bruce, J
    Gunnar, MR
    [J]. DEVELOPMENTAL PSYCHOBIOLOGY, 2002, 40 (01) : 43 - 56