Synthesis of 2,5-Disubstituted Isoxazolines Using Poly(ethylene glycol) as Soluble Polymer Support

被引：0

作者：

He, Xinwei ^{[1
]}

Jin, Jie ^{[1
]}

Wang, Cuie ^{[1
]}

Shang, Yongjia ^{[1
]}

机构：

[1] Anhui Normal Univ, Anhui Key Lab Funct Mol Solids, Coll Chem & Mat Sci, Wuhu 241000, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 29卷 / 01期

关键词：

poly(ethylene glycol); isoxazoline; liquid-phase organic synthesis; 1,3-dipolar cycloaddition; LIQUID-PHASE SYNTHESIS; ONE-POT SYNTHESIS; COMBINATORIAL SYNTHESIS; CYCLOADDITION; LIBRARY; PEG;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient liquid-phase synthesis of 2,5-disubstituted isoxazolines through a 1,3-dipolar cycloaddition is described. The poly(ethylene glycol) (PEG)-supported alkene reacted with nitrile oxides generated in situ from aldoximes, followed by cleavage from the PEG, to give isoxazolines in good yields and purities.

引用

页码：55 / 60

页数：6

共 34 条

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