Silicon array of elongated through-holes for monodisperse emulsion droplets

被引:203
作者
Kobayashi, I
Nakajima, M
Chun, K
Kikuchi, Y
Fukita, H
机构
[1] Natl Food Res Inst, Tsukuba, Ibaraki 3058642, Japan
[2] Univ Tsukuba, Inst Agr & Forest Engn, Tsukuba, Ibaraki 3058572, Japan
[3] Univ Tokyo, Inst Ind Sci, Tokyo 1538505, Japan
关键词
D O I
10.1002/aic.690480807
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
Monodisperse emulsions are of great significance in both scientific and industrial fields, since they have advantages such as their better stability and simplified physical properties. A novel micromachined emulsification device has been developed for monodisperse emulsion droplets. It has uniformly sized through-holes, called straightthrough microchannel (MC), on a silicon microchip. An oblong straightthrough MC successfully yielded monodisperse oil-in-water (O/W) emulsion droplets with an average droplet diameter of 32.5 mum and a coefficient of variation below 2% by forcing the dispersed phase into the continuous phase through the straightthrough MC. On the other hand, a circular straightthrough MC yielded polydisperse emulsion droplets. Straightthrough MC emulsification revealed that an elongated cross-sectional shape in the oblong straightthrough MC contributes significantly to the spontaneous formation of monodisperse emulsion droplets without any turbulent mixing.
引用
收藏
页码:1639 / 1644
页数:6
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