Scleritis complicating zoledronic acid infusion

被引：40

作者：

Benderson, David

Karakunnel, Joyson

Kathuria, Sajeev

Badros, Ashraf

机构：

[1] Univ Maryland, Greenebaum Canc Ctr, Baltimore, MD 21201 USA

[2] Univ Maryland, Dept Ophthalmol, Baltimore, MD 21201 USA

来源：

CLINICAL LYMPHOMA & MYELOMA | 2006年 / 7卷 / 02期

关键词：

bisphosphonates; multiple myeloma; ocular inflammation;

D O I：

10.3816/CLM.2006.n.053

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We present a case of severe unilateral posterior scleritis associated with zoledronic acid administration that was recognized and treated in a timely manner. Subsequent use of pamidronate was associated with milder inflammation in the same eye that eventually resolved with continued monthly infusions, indicating the possibility of immunologic tolerance. Physicians prescribing these drugs should be aware of this side effect, which, if not recognized and treated appropriately, is potentially devastating. We review the published data as well as the current treatment recommendations.

引用

收藏

页码：145 / 147

页数：3

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