Thermal Characteristics, Mechanical Properties, In Vitro Degradation and Cytotoxicity of Novel Biodegradable Zn-Al-Mg and Zn-Al-Mg-xBi Alloys

被引：45

作者：

Bakhsheshi-Rad, H. R. ^{[1
]}

Hamzah, E. ^{[2
]}

Low, H. T. ^{[2
]}

Cho, M. H. ^{[3
]}

Kasiri-Asgarani, M. ^{[1
]}

Farahany, S. ^{[4
]}

Mostafa, A. ^{[5
]}

Medraj, M. ^{[5
,6
]}

机构：

[1] Islamic Azad Univ, Najafabad Branch, Dept Mat Engn, Adv Mat Res Ctr, Najafabad, Iran

[2] Univ Teknol Malaysia, Fac Mech Engn, Dept Mat Mfg & Ind Engn, Johor Baharu 81310, Johor, Malaysia

[3] KISWIRE Sdn Bhd, Ctr Res & Dev, Johor Baharu, Johor, Malaysia

[4] Buein Zahra Tech Univ, Dept Mat & Mech Engn, Qazvin 3451745346, Iran

[5] Masdar Inst Sci & Technol, Dept Mech & Mat Engn, POB 54224, Masdar City, Abu Dhabi, U Arab Emirates

[6] Concordia Univ, Dept Mech Engn, 1455 De Maisonneuve Blvd West, Montreal, PQ H3G 1M8, Canada

来源：

ACTA METALLURGICA SINICA-ENGLISH LETTERS | 2017年 / 30卷 / 03期

关键词：

Zn-Al-Mg-Bi; Microstructure; Mechanical property; Corrosion; Cytotoxicity; CORROSION BEHAVIOR; MAGNESIUM ALLOYS; MICROSTRUCTURE; SR; CA; IMPLANTS; BISMUTH; DESIGN;

D O I：

10.1007/s40195-017-0534-2

中图分类号：

TF [冶金工业];

学科分类号：

0806 ;

摘要：

Ternary Zn-0.5Al-0.5Mg and quaternary Zn-0.5Al-0.5Mg-xBi (x = 0.1, 0.3 and 0.5) alloys were studied to evaluate the thermal and structural characteristics, mechanical properties, cytotoxicity and in vitro degradation behavior. Thermal analysis and microstructural observations showed that Zn-0.5Al-0.5Mg is composed of FCC-Al ? HCPZn + Mg-2(Zn, Al) 11 while a new phase a-Mg3Bi2 appeared after the addition of Bi to the Zn-0.5Al-0.5Mg ternary alloy. The results revealed that the quaternary Zn-Al-Mg-Bi alloys have higher tensile strength, elongation and hardness but slightly lower corrosion resistance than those of the ternary Zn-Al-Mg alloy. Based on the MTT assay, the Zn-Al-Mg and Zn-Al-Mg-Bi alloys were found to be biocompatible, and thus, they can be considered for further investigation in an in vivo environment.

引用

页码：201 / 211

页数：11

共 31 条

[1]

ASTM International, 2008, E8E8M08 ASTM

[2]

Bafandeh M.R., 2016, J ADV MAT PROCESS, V4, P3

[3] Synthesis and corrosion behavior of a hybrid bioceramic-biopolymer coating on biodegradable Mg alloy for orthopaedic implants [J].

Bakhsheshi-Rad, H. R. ;

Hamzah, E. ;

Ismail, A. F. ;

Sharer, Z. ;

Abdul-Kadir, M. R. ;

Daroonparvar, M. ;

Saud, Safaa N. ;

Medraj, M. .

JOURNAL OF ALLOYS AND COMPOUNDS, 2015, 648 :1067-1071

[4] Recent advances on the development of magnesium alloys for biodegradable implants [J].

Chen, Yongjun ;

Xu, Zhigang ;

Smith, Christopher ;

Sankar, Jag .

ACTA BIOMATERIALIA, 2014, 10 (11) :4561-4573

[5] Influence of thermal treatment on microstructure, mechanical and degradation properties of Zn-3Mg alloy as potential biodegradable implant material [J].

Dambatta, M. S. ;

Izman, S. ;

Kurniawan, D. ;

Farahany, Saeed ;

Yahaya, Bashir ;

Hermawan, H. .

MATERIALS & DESIGN, 2015, 85 :431-437

[6]

FACTSAGE, 2001, INT THERM DAT SYST

[7] An in vitro study on the cytotoxicity of bismuth oxychloride nanosheets in human HaCaT keratinocytes [J].

Gao, Xiaoya ;

Zhang, Xiaochao ;

Wang, Yawen ;

Wang, Yunfang ;

Peng, Shiqi ;

Fan, Caimei .

FOOD AND CHEMICAL TOXICOLOGY, 2015, 80 :52-61

[8] Microstructure, mechanical properties, corrosion behavior and cytotoxicity of Mg-Zn-Al-Ca alloys as biodegradable materials [J].

Homayun, Bahman ;

Afshar, Abdollah .

JOURNAL OF ALLOYS AND COMPOUNDS, 2014, 607 :1-10

[9] How useful is SBF in predicting in vivo bone bioactivity? [J].

Kokubo, T ;

Takadama, H .

BIOMATERIALS, 2006, 27 (15) :2907-2915

[10] Structure, mechanical characteristics and in vitro degradation, cytotoxicity, genotoxicity and mutagenicity of novel biodegradable Zn-Mg alloys [J].

Kubasek, J. ;

Vojtech, D. ;

Jablonska, E. ;

Pospisilova, I. ;

Lipov, J. ;

Ruml, T. .

MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2016, 58 :24-35

← 1 2 3 4 →