Self-compassion as a predictor of interleukin-6 response to acute psychosocial stress

被引:112
作者
Breines, Juliana G. [1 ]
Thoma, Myriam V.
Gianferante, Danielle
Hanlin, Luke
Chen, Xuejie
Rohleder, Nicolas
机构
[1] Brandeis Univ, Dept Psychol, MS 062,415 South St, Waltham, MA 02453 USA
关键词
Acute psychosocial stress; Inflammation; Interleukin-6; Self-compassion; Self-esteem; PSYCHOLOGICAL STRESS; GENE-EXPRESSION; SOCIAL SUPPORT; SHAME; REDUCTION; INCREASES; CORTISOL; PEOPLE; IMMUNE; THREAT;
D O I
10.1016/j.bbi.2013.11.006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We examined the hypothesis that self-compassion is associated with lower levels of stress-induced inflammation. On two consecutive days, plasma concentrations of interleukin-6 (IL-6) were assessed at baseline and at 30 and 120 min following exposure to a standardized laboratory stressor in a sample of 41 healthy young adults. Participants who were higher in self-compassion exhibited significantly lower day 1 IL-6 responses, even when controlling for self-esteem, depressive symptoms, demographic factors, and distress. Self-compassion was not related to day 2 IL-6 response but was inversely related to day 2 baseline IL-6 levels, and to increase in baseline IL-6 from day 1 to day 2. These findings suggest that self-compassion may serve as a protective factor against stress-induced inflammation and inflammation-related disease. (C) 2013 Elsevier Inc. All rights reserved.
引用
收藏
页码:109 / 114
页数:6
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