Assembly of DNA nanostructures with branched tris-DNA

被引：16

作者：

Kuroda, Takahiro ^{[1
]}

Sakurai, Yoshimasa ^{[1
]}

Suzuki, Yukinao ^{[1
]}

Nakamura, Akiko O. ^{[1
]}

Kuwahara, Masayasu ^{[1
]}

Ozaki, Hiroaki ^{[1
]}

Sawai, Hiroaki ^{[1
]}

机构：

[1] Gunma Univ, Fac Engn, Dept Appl Chem, Gunma 3768515, Japan

来源：

CHEMISTRY-AN ASIAN JOURNAL | 2006年 / 1卷 / 04期

关键词：

branched tris-DNA; DNA assembly; nanostructures; oligomerization; oligonucleotides;

D O I：

10.1002/asia.200600088

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Branched tris-DNA, in which two oligonucleotides of the same sequence and one other oligonucleotide of a different sequence are connected with a rigid central linker, was prepared chemically by using a DNA synthesizer. Two branched tris-DNA molecules with complementary DNA sequences form dimer and tetramer as well as linear and spherical oligomer complexes. The complex formation was studied by UV/thermal denaturation, enzyme digestion, gel electrophoresis, and AFM imaging.

引用

页码：575 / 580

页数：6

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