Biodegradability and biodegradation of poly(lactide)

被引：510

作者：

Tokiwa, Yutaka ^{[1
]}

Calabia, Buenaventurada P. ^{[1
]}

机构：

[1] Natl Inst Adv Ind Sci & Technol, AIST, Tsukuba Cent 6, Tsukuba, Ibaraki 3058566, Japan

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2006年 / 72卷 / 02期

关键词：

poly(lactide); biodegradability; biodegradation; amycolatopsis; protease; lipase;

D O I：

10.1007/s00253-006-0488-1

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Poly(lactide) (PLA) has been developed and made commercially available in recent years. One of the major tasks to be taken before the widespread application of PLA is the fundamental understanding of its biodegradation mechanisms. This paper provides a short overview on the biodegradability and biodegradation of PLA. Emphasis is focused mainly on microbial and enzymatic degradation. Most of the PLA-degrading microorganisms phylogenetically belong to the family of Pseudonocardiaceae and related genera such as Amycolatopsis, Lentzea, Kibdelosporangium, Streptoalloteichus, and Saccharothrix. Several proteinous materials such as silk fibroin, elastin, gelatin, and some peptides and amino acids were found to stimulate the production of enzymes from PLA-degrading microorganisms. In addition to proteinase K from Tritirachium album, subtilisin, a microbial serine protease and some mammalian serine proteases such as alpha-chymotrypsin, trypsin, and elastase could also degrade PLA.

引用

页码：244 / 251

页数：8

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