Green synthesis of silver nanoparticles using fruits extracts of Syzygium cumini and their bioactivity

The biosynthesis of silver nanoparticles have received great attention in the field of nanotechnology because of its antimicrobial and biomedical applications. In the current research scenario, the green synthesis of metal nanoparticles is expected to be cost-effective and environmentally benign alternative. In this effort, the fruit extracts from the Syzygium cumini was used as the reducing agent to synthesize silver nanoparticles (AgNPs) and the antioxidant, antibacterial, and anti-inflammatory properties of the synthesized nanoparticles have been evaluated. The synthesized Ag nanoparticles were characterized by UV-Visible spectroscopy (UV), Fourier-transform infrared spectroscopy (FTIR), Powder X-ray Diffraction (XRD) and scanning electron microscope (SEM).The formation of silver nanoparticles was confirmed by optical performance i.e change in color using UV-Visible spectroscopy showing a characteristic peak of silver nanoparticles at 443 nm. The presence of OH and C=O of plant secondary metabolites of Syzygium cumini were confirmed by FTIR spectroscopy, liable for capping and reduction of metal nanoparticles surface. Powder XRD analysis was used to analyze the crystal structure. This medicinal plant extract mediating green biosynthesized silver nanoparticles exhibited good in vitro-antioxidant, antibacterial and anti-inflammatory activities. Therefore, results of the present study highlights the synthesis of cost-effective, eco-friendly drugs with less side effects, which showed that there is the urge of in vivo studies at a molecular level to develop silver nanoparticles through greener approach using the medicinal plant (Syzygium cumini) extract as antibacterial, antioxidant, and anti-inflammatory agent for the treatment of bacterial infection, inflammation and many free radical oriented diseases.