Characterization of a novel polycystic kidney rat model with accompanying polycystic liver

被引：56
作者：
Katsuyama, M
Masuyama, T
Komura, I
Hibino, T
Takahashi, H
机构：
[1] Charles River Japan Inc, Kanagawa 2291124, Japan
[2] Ajinomoto Co Inc, Kawasaki Ku, Kawasaki, Kanagawa 2108681, Japan
[3] Fujita Hlth Univ, Ctr Lab Anim, Toyoake, Aichi 4701192, Japan
来源：
EXPERIMENTAL ANIMALS | 2000年 / 49卷 / 01期
关键词：
polycystic kidney; polycystic liver; rat;
D O I：
10.1538/expanim.49.51
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
A polycystic kidney rat model is being established from a Crj:CD (SD) rat strain. Unlike existing animal models of polycystic kidney disease, this mutant rat has a completely polycystic liver. Mating experiments revealed that the phenotype is controlled by an autosomal recessive gene. We propose that this gene be tentatively called the "rpc" gene.
引用
收藏
页码：51 / 55
页数：5
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