The Language Development Via FOXP2 in Autism Spectrum Disorder: A Review

被引：5

作者：

Chen, Panpan ^{[1
]}

Li, Zhongying ^{[1
]}

Li, Yanfei ^{[1
]}

Ahmad, Syed S. ^{[2
]}

Kamal, Mohammad A. ^{[3
,4
]}

Huo, Xiao ^{[5
]}

机构：

[1] Binzhou Peoples Hosp, Dept Pediat, Binzhou 256600, Shandong, Peoples R China

[2] Integral Univ, Fac Engn, Dept Bioengn, Lucknow, Uttar Pradesh, India

[3] King Abdulaziz Univ, King Fahd Med Res Ctr, POB 80216, Jeddah 21589, Saudi Arabia

[4] Enzymo Novel Global Community Educ Fdn, 7 Peterlee Pl, Hebersham, NSW 2770, Australia

[5] Second People Hosp Dezhou, Dept Pediat & Qual Control Off, 55 Fangzhi St, Dezhou City 253000, Shandong, Peoples R China

来源：

CURRENT PHARMACEUTICAL DESIGN | 2020年 / 26卷 / 37期

关键词：

autism; children; disease; FOXP2; language; teacher; SEVERE SPEECH; FORKHEAD-DOMAIN; CHILDREN; GENE; PERCEPTION; EXPRESSION; TARGETS;

D O I：

10.2174/1381612826666200909141108

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Background: An increasing number of newborn children in numerous nations are enrolled in early childhood education programs, and instructors, in this way, assume a focal job in invigorating language improvement in these youthful kids. Kids with language issues are found to have a higher risk for future scholarly challenges and learning inabilities. Language advancement among kids is an intricate procedure and vital for correspondence. The shortcomings in the utilization of grammatical structures may lessen the useful utilization of language for verbally expressive kids with autism spectrum disorder and exacerbate troubles with academic and social expertise advancement. Results: FOXP2, the single principal gene connected to a speech and language issue, is significant for the right execution of complex motor behaviors used for speech. In any case, changes in FOXP2 lead to a speech/language issue portrayed by childhood apraxia of speech. These days, language learning is fundamentally required for kids who need to move to different nations to pursue the instructive frameworks and be helpful individuals or residents of those nations. Conclusion: The purpose of this study was to explore the role of FOXP2 in language disorder and its management for childrens language and communication development.

引用

页码：4789 / 4795

页数：7

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