Vertebrate pseudogenes

被引：355
作者：
Mighell, AJ
Smith, NR
Robinson, PA
Markham, AF
机构：
[1] Univ Leeds, St James Hosp, Mol Med Unit, Leeds LS9 7TF, W Yorkshire, England
[2] Univ Leeds, Leeds Dent Inst, Leeds LS2 9LU, W Yorkshire, England
来源：
FEBS LETTERS | 2000年 / 468卷 / 2-3期
关键词：
pseudogene; retrotransposon; human genome; transcription;
D O I：
10.1016/S0014-5793(00)01199-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Pseudogenes are commonly encountered during investigation of the genomes of a Hide range of life forms. This review concentrates on vertebrate, and in particular mammalian, pseudogenes and describes their origin and subsequent evolution. Consideration is also given to pseudogenes that are transcribed and to the unusual group of genes that exist at the interface between functional genes and non-functional pseudogenes. As the sequences of different genomes are characterised, the recognition and interpretation of pseudogene sequences will become more important and have a greater impact in the field of molecular genetics. (C) 2000 Federation of European Biochemical Societies.
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页码：109 / 114
页数：6
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