Mediterranean-Style Diet for the Primary and Secondary Prevention of Cardiovascular Disease: A Cochrane Review

被引：33

作者：

Rees, Karen ^{[1
]}

Takeda, Andrea ^{[2
]}

Martin, Nicole ^{[2
]}

Ellis, Leila ^{[1
]}

Wijesekara, Dilini ^{[1
]}

Vepa, Abhinav ^{[1
]}

Das, Archik ^{[1
]}

Hartley, Louise ^{[3
]}

Stranges, Saverio ^{[4
,5
,6
]}

机构：

[1] Univ Warwick, Warwick Med Sch, Div Hlth Sci, Coventry, W Midlands, England

[2] UCL, Inst Hlth Informat Res, London, England

[3] RTI Hlth Solut, Manchester, Lancs, England

[4] Western Univ, Schulich Sch Med & Dent, Dept Epidemiol & Biostat, London, ON, Canada

[5] Western Univ, Schulich Sch Med & Dent, Dept Family Med, London, ON, Canada

[6] Luxembourg Inst Hlth, Dept Populat Hlth, Strassen, Luxembourg

来源：

GLOBAL HEART | 2020年 / 15卷 / 01期

关键词：

Mediterranean dietary pattern; Cardiovascular disease; Cardiovascular risk factors; Primary Prevention; Secondary Prevention; Systematic Review; RISK-FACTORS; MYOCARDIAL-INFARCTION; LOW-FAT; CARDIOPROTECTIVE DIET; METABOLIC SYNDROME; HEALTHY-ADULTS; OLIVE OIL; ADHERENCE; INTERVENTION; INFLAMMATION;

D O I：

10.5334/gh.853

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Diet plays a major role in cardiovascular disease (CVD) risk. Objectives: To determine the effectiveness of a Mediterranean-style diet for the primary and secondary prevention of CVD. Methods: We searched for randomised controlled trials (RCTs) of Mediterranean-style diets in healthy adults and those at increased risk of CVD (primary prevention) and with established CVD (secondary prevention). Results: Thirty RCTs were included, 22 in primary prevention and eight in secondary prevention. Clinical endpoints were reported in two trials where there was moderate quality evidence for a reduction in strokes for primary prevention, and low quality evidence for a reduction in total and CVD mortality in secondary prevention. We found moderate quality evidence of improvement in CVD risk factors for primary prevention and low quality evidence of little or no effect in secondary prevention. Conclusions: There is still some uncertainty regarding the effects of a Mediterranean-style diet in CVD prevention.

引用

页数：29

共 66 条

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