230 days of ultra long-term subcutaneous EEG: seizure cycle analysis and comparison to patient diary

被引：54

作者：

Viana, Pedro F. ^{[1
,2
]}

Duun-Henriksen, Jonas ^{[3
]}

Glassteter, Martin ^{[4
]}

Duempelmann, Matthias ^{[4
]}

Nurse, Ewan S. ^{[5
,6
]}

Martins, Isabel P. ^{[2
]}

Dumanis, Sonya B. ^{[7
]}

Schulze-Bonhage, Andreas ^{[4
]}

Freestone, Dean R. ^{[5
,6
]}

Brinkmann, Benjamin H. ^{[8
]}

Richardson, Mark P. ^{[1
]}

机构：

[1] Kings Coll London, Inst Psychiat Psychol & Neurosci, London, England

[2] Univ Lisbon, Fac Med, Lisbon, Portugal

[3] UNEEG Med AS, Lynge, Denmark

[4] Univ Med Ctr Freiburg, Dept Neurosurg, Epilepsy Ctr, Freiburg, Germany

[5] Seer Med Inc, Melbourne, Vic, Australia

[6] Univ Melbourne, St Vincents Hosp, Dept Med, Melbourne, Vic, Australia

[7] Epilepsy Fdn, Landover, MD USA

[8] Mayo Clin, Dept Neurol, Dept Physiol & Biomed Engn, Mayo Syst Electrophysiol Lab, Rochester, MN USA

来源：

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY | 2021年 / 8卷 / 01期

基金：

英国工程与自然科学研究理事会;

关键词：

EPILEPSY; SYSTEM;

D O I：

10.1002/acn3.51261

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We describe the longest period of subcutaneous EEG (sqEEG) monitoring to date, in a 35-year-old female with refractory epilepsy. Over 230 days, 4791/5520 h of sqEEG were recorded (86%, mean 20.8 [IQR 3.9] hours/day). Using an electronic diary, the patient reported 22 seizures, while automatically-assisted visual sqEEG review detected 32 seizures. There was substantial agreement between days of reported and recorded seizures (Cohen's kappa 0.664), although multiple clustered seizures remained undocumented. Circular statistics identified significant sqEEG seizure cycles at circadian (24-hour) and multidien (5-day) timescales. Electrographic seizure monitoring and analysis of long-term seizure cycles are possible with this neurophysiological tool.

引用

页码：288 / 293

页数：6

共 16 条

[1] Multi-day rhythms modulate seizure risk in epilepsy [J].

Baud, Maxime O. ;

Kleen, Jonathan K. ;

Mirro, Emily A. ;

Andrechak, Jason C. ;

King-Stephens, David ;

Chang, Edward F. ;

Rao, Vikram R. .

NATURE COMMUNICATIONS, 2018, 9

[2] Seizure detection using scalp-EEG [J].

Baumgartner, Christoph ;

Koren, Johannes P. .

EPILEPSIA, 2018, 59 :14-22

[3] Prediction of seizure likelihood with a long-term, implanted seizure advisory system in patients with drug-resistant epilepsy: a first-in-man study [J].

Cook, Mark J. ;

O'Brien, Terence J. ;

Berkovic, Samuel F. ;

Murphy, Michael ;

Morokoff, Andrew ;

Fabinyi, Gavin ;

D'Souza, Wendyl ;

Yerra, Raju ;

Archer, John ;

Litewka, Lucas ;

Hosking, Sean ;

Lightfoot, Paul ;

Ruedebusch, Vanessa ;

Sheffield, W. Douglas ;

Snyder, David ;

Leyde, Kent ;

Himes, David .

LANCET NEUROLOGY, 2013, 12 (06) :563-571

[4]

Devinsky O, 2016, LANCET NEUROL, V15, P1075, DOI 10.1016/S1474-4422(16)30158-2

[5] Seizure Forecasting from Idea to Reality. Outcomes of the My Seizure Gauge Epilepsy Innovation Institute Workshop [J].

Dumanis, Sonya B. ;

French, Jaqueline A. ;

Bernard, Christophe ;

Worrell, Gregory A. ;

Fureman, Brandy E. .

ENEURO, 2017, 4 (06)

[6] EEG Signal Quality of a Subcutaneous Recording System Compared to Standard Surface Electrodes [J].

Duun-Henriksen, Jonas ;

Kjaer, Troels Wesenberg ;

Looney, David ;

Atkins, Mary Doreen ;

Sorensen, Jens Ahm ;

Rose, Martin ;

Mandic, Danilo P. ;

ElsborgMadsen, Rasmus ;

Juhl, Claus Bogh .

JOURNAL OF SENSORS, 2015, 2015

[7] Diagnostic challenges in epilepsy: seizure under-reporting and seizure detection [J].

Elger, Christian E. ;

Hoppe, Christian .

LANCET NEUROLOGY, 2018, 17 (03) :279-288

[8] Circadian and circaseptan rhythms in human epilepsy: a retrospective cohort study [J].

Karoly, Philippa J. ;

Goldenholz, Daniel M. ;

Freestone, Dean R. ;

Moss, Robert E. ;

Grayden, David B. ;

Theodore, William H. ;

Cook, Mark J. .

LANCET NEUROLOGY, 2018, 17 (11) :977-985

[9] The circadian profile of epilepsy improves seizure forecasting [J].

Karoly, Philippa J. ;

Ung, Hoameng ;

Grayden, David B. ;

Kuhlmann, Levin ;

Leyde, Kent ;

Cook, Mark J. ;

Freestone, Dean R. .

BRAIN, 2017, 140 :2169-2182

[10]

KAROLY PJ, 2020, EPILEPSIA 0327, P1, DOI DOI 10.1111/EPI.16485

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