Cyclic peptide alkaloids from the bark of Discaria americana

被引：27

作者：

Giacomelli, SR ^{[1
]}

Maldaner, G ^{[1
]}

Gonzaga, WA ^{[1
]}

Garcia, CM ^{[1
]}

da Silva, UF ^{[1
]}

Dalcol, II ^{[1
]}

Morel, AF ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Dept Quim, BR-97105900 Santa Maria, RS, Brazil

来源：

PHYTOCHEMISTRY | 2004年 / 65卷 / 07期

关键词：

Discaria americana; Rhamnaceae; cyclic peptides; antibacterial activity;

D O I：

10.1016/j.phytochem.2004.02.006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The isolation and structure determination of cyclic peptide alkaloids, discarine-M and discarine-N, along with seven known cyclic peptide alkaloids, adouetine-Y', franganine, frangulanine, discarines-A, -B, -C, and -D from the root bark of Discaria americana are described. Structures were determined spectroscopically, especially using 2D NMR spectroscopic analysis. The crude methanol extract, the basic ether extract, and the alkaloids 6 and 7 also weakly inhibited growth of gram-negative and gram-positive bacteria. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：933 / 937

页数：5

共 50 条

[41] The Emergence of Cyclic Peptides: The Potential of Bioengineered Peptide Drugs
Thapa, Parashar
Espiritu, Michael J.
Cabalteja, Chino
Bingham, Jon-Paul
INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2014, 20 (04) : 545 - 551
[42] The Emergence of Cyclic Peptides: The Potential of Bioengineered Peptide Drugs
Parashar Thapa
Michael J. Espiritu
Chino Cabalteja
Jon-Paul Bingham
International Journal of Peptide Research and Therapeutics, 2014, 20 : 545 - 551
[43] Controlled Construction of Cyclic d / l Peptide Nanorods
Silk, Mitchell R.
Mohanty, Biswaranjan
Sampson, Joanne B.
Scanlon, Martin J.
Thompson, Philip E.
Chalmers, David K.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 58 (02) : 596 - 601
[44] Two new 5(14)-membered type cyclopeptide alkaloids from root bark of Ziziphus spina-christi (L.) Desf.
Adam, Ibrahim Abdurrahman
Irshad, Rimsha
Atia-tul-Wahab
Omoboyowa, Damilola Alex
Choudhary, M. Iqbal
Wang, Yan
NATURAL PRODUCT RESEARCH, 2023, 37 (15) : 2473 - 2479
[45] Diffusible factors from Frankia modify nodulation kinetics in Discaria trinervis, an intercellular root-infected actinorhizal symbiosis
Andres Gabbarini, Luciano
Gabriel Wall, Luis
FUNCTIONAL PLANT BIOLOGY, 2011, 38 (8-9) : 662 - 670
[46] Parallel Versus Antiparallel β-Sheet Structure in Cyclic Peptide Hybrids Containing γ- or δ-Cyclic Amino Acids
Calvelo, Martin
Lamas, Alejandro
Guerra, Arcadio
Amorin, Manuel
Garcia-Fandino, Rebeca
Granja, Juan R.
CHEMISTRY-A EUROPEAN JOURNAL, 2020, 26 (26) : 5846 - 5858
[47] Form and Function in Cyclic Peptide Natural Products: A Pharmacokinetic Perspective
Bockus, Andrew T.
McEwen, Cayla M.
Lokey, R. Scott
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2013, 13 (07) : 821 - 836
[48] Synthesis of Cyclic Peptide Mimetics by the Successive Ring Expansion of Lactams
Stephens, Thomas C.
Lodi, Mahendar
Steer, Andrew M.
Lin, Yun
Gill, Matthew T.
Unsworth, William P.
CHEMISTRY-A EUROPEAN JOURNAL, 2017, 23 (54) : 13314 - 13318
[49] Cyclic Peptide-Gadolinium Nanoparticles for Enhanced Intracellular Delivery
Shirazi, Amir Nasrolahi
Park, Shang Eun
Rad, Shirin
Baloyan, Luiza
Mandal, Dindyal
Sajid, Muhammad Imran
Hall, Ryley
Lohan, Sandeep
Zoghebi, Khalid
Parang, Keykavous
Tiwari, Rakesh Kumar
PHARMACEUTICS, 2020, 12 (09) : 1 - 15
[50] Cyclic Peptide-Gadolinium Nanocomplexes as siRNA Delivery Tools
Nasrolahi Shirazi, Amir
Sajid, Muhammad Imran
Mandal, Dindyal
Stickley, David
Nagasawa, Stephanie
Long, Joshua
Lohan, Sandeep
Parang, Keykavous
Tiwari, Rakesh Kumar
PHARMACEUTICALS, 2021, 14 (11)

← 1 2 3 4 5 →