Synthesis and biological activity of high-molecular N-glycosides

被引：1
|
作者：
Shul'tsev, A. L. [1 ]
机构：
[1] Russian Acad Sci, Inst Macromol Cpds, St Petersburg 199004, Russia
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2015年 / 85卷 / 10期
关键词：
p-aminostyrene; N-glycosides; carbon chain polymers; biological activity;
D O I：
10.1134/S1070363215100229
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new synthetic approach to high molecular N-glycosides has been developed on the basis of radical polymerization of vinyl-containing N-glycosides. Homo- and copolymers derived from N-(D-glucopyranosyl)-, N-(D-mannopyranosyl)-, and N-(L-rhamnopyranosyl)-4-vinylaniline have been synthesized and characterized. It has been found for the first time that polymeric N-glycosides exhibit antibacterial and immunomodulatory activity.
引用
收藏
页码：2361 / 2365
页数：5
相关论文
共 50 条
  • [31] Enzymatic synthesis of glycosides: from natural O- and N-glycosides to rare C- and S-glycosides
    Ati, Jihen
    Lafite, Pierre
    Daniellou, Richard
    BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2017, 13 : 1857 - 1865
  • [32] HPLC analysis for amobarbital N-glycosides in urine
    Nandi, V
    Soine, WH
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1997, 15 (08) : 1187 - 1195
  • [33] SYNTHESES OF HETEROCYCLIC O- AND N-GLYCOSIDES
    PFLEIDER.W
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 1965, 4 (03) : 261 - &
  • [34] Synthesis and Preliminary Anticancer Activity Assessment of N-Glycosides of 2-Amino-1,3,4-thiadiazoles
    Zurawska, Katarzyna
    Stokowy, Marcin
    Kapica, Patryk
    Olesiejuk, Monika
    Kudelko, Agnieszka
    Papaj, Katarzyna
    Skonieczna, Magdalena
    Szeja, Wieslaw
    Walczak, Krzysztof
    Kasprzycka, Anna
    MOLECULES, 2021, 26 (23):
  • [35] Synthesis, characterization, and biological evaluation of new N-glycosides derived from O-pivaloylated β-d-glucopyranosylamine
    Chao Shen
    Guobin Zhou
    Xinzhi Chen
    Pengfei Zhang
    Research on Chemical Intermediates, 2012, 38 : 863 - 870
  • [36] SYNTHESIS OF HIGH-MOLECULAR ORGANOSILICON POLYRADICALS
    KONOBEEVSKII, KS
    VDOVIN, VM
    NAMETKIN, NS
    FINKELSH.ES
    IVANOV, VP
    VYSOKOMOLEKULYARNYE SOEDINENIYA SECTION B, 1972, 14 (11): : 811 - +
  • [37] Synthesis, characterization, and biological evaluation of new N-glycosides derived from O-pivaloylated β-D-glucopyranosylamine
    Shen, Chao
    Zhou, Guobin
    Chen, Xinzhi
    Zhang, Pengfei
    RESEARCH ON CHEMICAL INTERMEDIATES, 2012, 38 (3-5) : 863 - 870
  • [38] Design, synthesis and in vivo hypoglycemic activity of tetrazole-bearing N-glycosides as SGLT2 inhibitors
    Gao, Y. L.
    Zhao, G. L.
    Liu, W.
    Shao, H.
    Wang, Y. L.
    Xu, W. R.
    Tang, L. D.
    Wang, J. W.
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 2010, 49 (11): : 1499 - 1508
  • [39] LONG-CHAIN ALKYLUREA N-GLYCOSIDES
    ERICKSON, JG
    KEPS, JS
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1953, 75 (17) : 4339 - 4339
  • [40] PREPARATION AND STRUCTURE OF PHOSPHONO SUGAR N-GLYCOSIDES
    YAMASHITA, M
    IIDA, A
    IKAI, K
    OSHIKAWA, T
    HANAYA, T
    YAMAMOTO, H
    CHEMISTRY LETTERS, 1992, (03) : 407 - 410
12345