Synthesis and biological activity of high-molecular N-glycosides

被引:1
|
作者
Shul'tsev, A. L. [1 ]
机构
[1] Russian Acad Sci, Inst Macromol Cpds, St Petersburg 199004, Russia
关键词
p-aminostyrene; N-glycosides; carbon chain polymers; biological activity;
D O I
10.1134/S1070363215100229
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new synthetic approach to high molecular N-glycosides has been developed on the basis of radical polymerization of vinyl-containing N-glycosides. Homo- and copolymers derived from N-(D-glucopyranosyl)-, N-(D-mannopyranosyl)-, and N-(L-rhamnopyranosyl)-4-vinylaniline have been synthesized and characterized. It has been found for the first time that polymeric N-glycosides exhibit antibacterial and immunomodulatory activity.
引用
收藏
页码:2361 / 2365
页数:5
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