Antioxidant and cytotoxic activities investigation of tomato seed extracts

被引：9

作者：

Tommonaro, Giuseppina ^{[1
]}

Caporale, Angelamaria ^{[2
]}

De Martino, Laura ^{[2
]}

Popolo, Ada ^{[2
]}

De Prisco, Rocco ^{[1
]}

Nicolaus, Barbara ^{[1
]}

Abbamondi, Gennaro Roberto ^{[1
]}

Saturnino, Carmela ^{[2
]}

机构：

[1] Natl Res Council Italy, Inst Biomol Chem, I-80078 Pozzuoli, NA, Italy

[2] Univ Salerno, Dept Farmacy, I-84084 Fisciano, SA, Italy

来源：

NATURAL PRODUCT RESEARCH | 2014年 / 28卷 / 10期

关键词：

Tomato; antioxidant activity; cytotoxicity; seed extracts; PREVENTION; LYCOPENE; CANCER;

D O I：

10.1080/14786419.2013.879474

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Biological activities of different varieties of tomato seed extracts were evaluated to verify the potential antioxidant and/or antiproliferative activity of the bioactive metabolites present in them. Findings demonstrated that among all the varieties investigated (San Marzano Rosso, San Marzano Giallo, Corbarino, Black Tomato and San Marzano/Black Tomato hybrid) San Marzano Rosso seed extract exhibited the highest free radical-scavenging activity with 68% of 2,2-Diphenyl-1-picrylhydrazyl radical inhibition, and the best cytotoxic activity evaluated by using the brine shrimp test (LD50: 23,198ppm) and 3-(4,5-dimethylthiazol-2-yl)-2,5-phenyl-2H-tetrazolium bromide assay on A375 cell line (IC50: 137.7g/mL).

引用

页码：764 / 768

页数：5

共 50 条

[21] Comparison of the Antioxidant and Cytotoxic Activities of Phyllanthus virgatus and Phyllanthus amarus Extracts
Poompachee, Kanchana
Chudapongse, Nuannoi
MEDICAL PRINCIPLES AND PRACTICE, 2011, 21 (01) : 24 - 29
[22] Cytotoxic, Antioxidant, and Metabolic Enzyme Inhibitory Activities of Euphorbia cyparissias Extracts
Alonazi, Mona
Horchani, Habib
Alwhibi, Mona
Ben Bacha, Abir
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2020, 2020
[23] Antioxidant, Antimicrobial and Cytotoxic Activities of Salvia verticillata L. Extracts
Barjaktarevic, Ana
Cirovic, Tijana
Arsenijevic, N.
Volarevic, V.
Markovic, Bojana Simovic
Mitic, Violeta
Jovanovic, Vesna Stankov
Cupara, Snezana
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 83 (06) : 1280 - 1287
[24] Bioactive compounds and antioxidant, antimicrobial and cytotoxic activities of extracts of Curcuma longa
Dusman Tonin, Lilian Tatiani
Volpato de Oliveira, Taila Fernanda
de Marco, Inara Giacobbo
Palioto, Graciana Freitas
Dusman, Elisangela
JOURNAL OF FOOD MEASUREMENT AND CHARACTERIZATION, 2021, 15 (04) : 3752 - 3760
[25] Antioxidant Activities of the Phenolic Extracts of Seed Oils and Seed Hulls of Five Plant Species
Seneviratne, K. N.
Kotuwegedara, R. T.
FOOD SCIENCE AND TECHNOLOGY INTERNATIONAL, 2009, 15 (05) : 419 - 425
[26] Evaluation of Antimicrobial, Antioxidant and Cytotoxic Activities of Dialium cochinchinensis Seed Extract
Bui, L. T. K.
Nguyen, Q. T.
Dao, L. M.
Nguyen, H. L.
Lam, M. V.
Hoang, C. T.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2019, 81 (05) : 975 - 980
[27] Antibacterial and Antioxidant Activities of Prinsepia utilis Royle Leaf and Seed Extracts
Bagale, Rakshya
Acharya, Srijana
Gupta, Akriti
Chaudhary, Pooja
Chaudhary, Gautam Prasad
Pandey, Jitendra
JOURNAL OF TROPICAL MEDICINE, 2022, 2022
[28] Antioxidant activities of red pepper (Capsicum annuum) pericarp and seed extracts
Sim, Ki Hyeon
Sil, Han Young
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY, 2008, 43 (10): : 1813 - 1823
[29] Studies on antioxidant and cyclooxygenase inhibition activities of Eriobotrya japonica seed extracts
Zhou, L., 1600, Chinese Institute of Food Science and Technology (13):
[30] The role of dietary chlorophylls: an EPR study on the antioxidant activities of tomato lipid extracts
Sgherri, C.
Pinzino, C.
Izzo, R.
AGROCHIMICA, 2011, 55 (05): : 249 - 260

← 1 2 3 4 5 →