Chordoma of vagina: a case report and review of the literature

Chordoma is a rare, low-grade malignant tumor originating from the notochordal remnant, usually located in axial skeleton, especially sacral and cranial. Chordoma of vagina is extremely rare and has never been reported up to now. In this case report, we discuss the clinical characteristics, diagnosis and therapeutic strategies of vaginal chordoma combined with literature review, to further explore the features of vaginal chordoma and raise awareness of vaginal neoplasms. A 58-year-old woman presented with a three year history of vaginal mass and a 6 day history of colporrhagia after menopause for 16 years. After the surgical excision, the histopathological examination and immunohistochemical confirmed it to be vaginal chordoma. With one year follow-up, local recurrence and metastasis has not yet been observed.