An efficient synthesis of conformationally restricted peptides containing beta-aminocyclopropanecarboxylic acids

被引：0
作者：
Voigt, J
Noltemeyr, M
Reiser, O
机构：
[1] UNIV GOTTINGEN,INST ORGAN CHEM,D-37077 GOTTINGEN,GERMANY
[2] UNIV GOTTINGEN,INST ANORGAN CHEM,D-37077 GOTTINGEN,GERMANY
[3] UNIV STUTTGART,INST ORGAN CHEM & ISOTOPENFORSCH,D-70569 STUTTGART,GERMANY
来源：
SYNLETT | 1997年 / 02期
关键词：
peptides; beta-amino acids; pyrrole; cyclopropanation; oxidation;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new synthetic approach for the synthesis of diastereo- and enantiomerically pure peptides having a cis-beta-aminocyclopropanecarboxylic acid incorporated was developed.
引用
收藏
页码：202 / &
页数：4
相关论文
共 12 条
[1]  
BLASIO BD, 1991, BIOPOLYMERS, V31, P1181
[2]  
CABRELE C, UNPUB
[3]   RING-OPENING REACTIONS OF CERTAIN 2-CARBONYL-SUBSTITUTED CYCLOPROPYLAMINES [J].
CANNON, JG ;
GARST, JE .
JOURNAL OF ORGANIC CHEMISTRY, 1975, 40 (02) :182-184
[4]  
Lombardi A, 1996, BIOPOLYMERS, V38, P693, DOI 10.1002/(SICI)1097-0282(199602)38:6<693::AID-BIP2>3.0.CO
[5]  
2-Q
[6]  
PAULINI K, 1994, LIEBIGS ANN CHEM, P549
[7]  
PAULINI K, 1991, LIEBIGS ANN CHEM, P455
[8]   CYCLIC BETA-ALANYL-BETA-ALANINE CONTAINING PEPTIDES - A NEW MOLECULAR TOOL FOR BETA-TURNED PEPTIDES [J].
PAVONE, V ;
LOMBARDI, A ;
YANG, X ;
PEDONE, C ;
DIBLASIO, B .
BIOPOLYMERS, 1990, 30 (1-2) :189-196
[9]   BETA-ALANINE CONTAINING PEPTIDES - A NOVEL MOLECULAR TOOL FOR THE DESIGN OF GAMMA-TURNS [J].
PAVONE, V ;
LOMBARDI, A ;
DAURIA, G ;
SAVIANO, M ;
NASTRI, F ;
PAOLILLO, L ;
DIBLASIO, B ;
PEDONE, C .
BIOPOLYMERS, 1992, 32 (02) :173-183
[10]   beta-peptides: Synthesis by Arndt-Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X-ray crystallography. Helical secondary structure of a beta-hexapeptide in solution and its stability towards pepsin [J].
Seebach, D ;
Overhand, M ;
Kuhnle, FNM ;
Martinoni, B ;
Oberer, L ;
Hommel, U ;
Widmer, H .
HELVETICA CHIMICA ACTA, 1996, 79 (04) :913-941
12