PD-L1 status and versican proteolysis predict CD8+ T cell infiltration in esophageal cancer

被引：0
|
作者：
Emmerich, Phillip B. [1 ]
Witt, Jacob [1 ]
Buehler, Darya [1 ]
Depke, Mitchell [1 ]
Verhagen, Nathaniel [1 ]
Clipson, Linda [1 ]
Matkowskyj, Kristina [2 ]
Uboha, Nataliya [1 ]
Baschnagel, Andrew [1 ]
Deming, Dustin [1 ]
机构：
[1] Univ Wisconsin, Madison, WI USA
[2] UW Sch Med & Publ Hlth, Madison, WI USA
来源：
CANCER RESEARCH | 2020年 / 80卷 / 16期
关键词：
D O I：
10.1158/1538-7445.AM2020-3294
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3294
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Extracellular vesicles containing PD-L1 contribute to CD8+ T-cell immune suppression and predict poor outcomes in small cell lung cancer
    Dou, Xiaoyan
    Hua, Yan
    Chen, Zhaowu
    Chao, Fengmei
    Li, Ming
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2022, 207 (03): : 307 - 317
  • [22] PD-L1 expression level and CD8+/FoxP3+ T cell ratio in breast cancer and prognosis
    Hattori, Masaya
    Khramtsova, Galina
    Sveen, Lise
    Yoshimatsu, Toshio
    Huo, Dezheng
    Olopade, Olufunmilayo I.
    CANCER RESEARCH, 2019, 79 (13)
  • [23] Anlotinib enhanced CD8+ T cell infiltration via induction of CCL5 improves the efficacy of PD-1/PD-L1 blockade therapy in lung cancer
    Luo, Jie
    Cheng, Kebin
    Ji, Xianxiu
    Gao, Caixia
    Zhu, Ren
    Chen, Jiayi
    Xue, Wenjun
    Huang, Qi
    Xu, Qingqiang
    CANCER LETTERS, 2024, 591
  • [24] Tumor PD-L1 status and CD8+ tumor-infiltrating T cells: markers of improved prognosis in oropharyngeal cancer
    De Meulenaere, Astrid
    Vermassen, Tijl
    Aspeslagh, Sandrine
    Deron, Philippe
    Duprez, Frederic
    Laukens, Debby
    Van Dorpe, Jo
    Ferdinande, Liesbeth
    Rottey, Sylvie
    ONCOTARGET, 2017, 8 (46) : 80443 - 80452
  • [25] Classification of gallbladder cancer by assessment of CD8+ TIL and PD-L1 expression
    Jianzhen Lin
    Junyu Long
    Xueshuai Wan
    Jingci Chen
    Yi Bai
    Anqiang Wang
    Xiaobo Yang
    Yan Wu
    Simon C. Robson
    Xinting Sang
    Haitao Zhao
    BMC Cancer, 18
  • [26] Classification of gallbladder cancer by assessment of CD8+ TIL and PD-L1 expression
    Lin, Jianzhen
    Long, Junyu
    Wan, Xueshuai
    Chen, Jingci
    Bai, Yi
    Wang, Anqiang
    Yang, Xiaobo
    Wu, Yan
    Robson, Simon C.
    Sang, Xinting
    Zhao, Haitao
    BMC CANCER, 2018, 18
  • [27] Concurrent High PD-L1 Expression and CD8+ Immune Cell Infiltration Predict PD-1 Blockade Efficacy in Advanced EGFR-Mutant NSCLC Patients
    Shimoda, Yukiko
    Shibaki, Ryota
    Yoshida, Tatsuya
    Murakami, Shuji
    Shirasawa, Masayuki
    Torasawa, Masahiro
    Matsumoto, Yuji
    Masuda, Ken
    Shinno, Yuki
    Okuma, Yusuke
    Goto, Yasushi
    Horinouchi, Hidehito
    Yamamoto, Noboru
    Ohe, Yuichiro
    Motoi, Noriko
    CLINICAL LUNG CANCER, 2022, 23 (06) : 477 - 486
  • [28] Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T Cell Responses
    Cousin, Nikola
    Cap, Stefan
    Dihr, Manuel
    Tacconi, Carlotta
    Detmar, Michael
    Dieterich, Lothar C.
    JOURNAL OF VASCULAR RESEARCH, 2021, 58 : 8 - 8
  • [29] TGFβ-dependent expression of PD-1 and PD-L1 controls CD8+ T cell anergy in transplant tolerance
    Baas, Marije
    Besancon, Alix
    Goncalves, Tania
    Valette, Fabrice
    Yagita, Hideo
    Sawitzki, Birgit
    Volk, Hans-Dieter
    Waeckel-Enee, Emmanuelle
    Rocha, Benedita
    Chatenoud, Lucienne
    You, Sylvaine
    ELIFE, 2016, 5
  • [30] Regulatory mechanisms of PD-1/PD-L1 pathway on CD8+ T cell activation in murine contact hypersensitivity
    Hirano, T.
    Honda, T.
    Tamada, K.
    Chen, L.
    Kabashima, K.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2017, 137 (05) : S5 - S5
12345