SplicePlot: a utility for visualizing splicing quantitative trait loci

被引：9

作者：

Wu, Eric ^{[1
]}

Nance, Tracy ^{[1
]}

Montgomery, Stephen B. ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Dept Pathol, Stanford, CA 94305 USA

来源：

BIOINFORMATICS | 2014年 / 30卷 / 07期

关键词：

RNA;

D O I：

10.1093/bioinformatics/btt733

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA sequencing has provided unprecedented resolution of alternative splicing and splicing quantitative trait loci (sQTL). However, there are few tools available for visualizing the genotype-dependent effects of splicing at a population level. SplicePlot is a simple command line utility that produces intuitive visualization of sQTLs and their effects. SplicePlot takes mapped RNA sequencing reads in BAM format and genotype data in VCF format as input and outputs publication-quality Sashimi plots, hive plots and structure plots, enabling better investigation and understanding of the role of genetics on alternative splicing and transcript structure.

引用

页码：1025 / 1026

页数：2

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