Matrix-assisted laser desorption/ionization by using femtosecond laser pulses in the near-infrared wavelength regime

被引：10

作者：

Wichmann, J. M. ^{[1
]}

Lupulescu, C. ^{[1
]}

Woeste, L. ^{[1
]}

Lindinger, A. ^{[1
]}

机构：

[1] Free Univ Berlin, Inst Expt Phys, D-14195 Berlin, Germany

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2009年 / 23卷 / 08期

关键词：

FLIGHT MASS-SPECTROMETRY; MALDI MATRIX; IONIZATION MECHANISMS; GAS-PHASE; DESORPTION; ABSORPTION; DEPENDENCE; MOLECULES;

D O I：

10.1002/rcm.3974

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We observe a substantial matrix-assisted laser desorption/ionization (MALDI) signal when irradiating femtosecond laser pulses in the near-infrared spectral range centered around 800 nm and using standard MALDI matrices with absorption bands in the ultraviolet (UV) regime. The laser pulse energy dependence of this novel phenomenon is investigated in comparison with MALDI with near-UV laser pulses. Our observations show that multiphoton absorption/ionization could be a major issue among the MALDI processes when the sample is irradiated with ultra-short laser pulses. Copyright (C) 2009 John Wiley & Sons, Ltd.

引用

页码：1105 / 1108

页数：4

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