Free-living amoebae, a training field for macrophage resistance of mycobacteria

被引:95
作者
Salah, I. B. [1 ]
Ghigo, E. [1 ]
Drancourt, M. [1 ]
机构
[1] Univ Mediterranee, URMITE, Fac Med, CNRS 6236 IRD 198,IFR 48, Marseille 5, France
关键词
Acanthamoebae; free-living amoebae (FLA); interaction; Mycobacterium; review; AVIUM SUBSP PARATUBERCULOSIS; ACANTHAMOEBA-CASTELLANII; RESISTING BACTERIA; DICTYOSTELIUM-DISCOIDEUM; INTRACELLULAR PERSISTENCE; PHAGOLYSOSOME BIOGENESIS; LEGIONELLA-PNEUMOPHILA; EARLY ENDOSOMES; GENE-TRANSFER; MARINUM;
D O I
10.1111/j.1469-0691.2009.03011.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
P>Mycobacterium species evolved from an environmental recent common ancestor by reductive evolution and lateral gene transfer. Strategies selected through evolution and developed by mycobacteria resulted in resistance to predation by environmental unicellular protists, including free-living amoebae. Indeed, mycobacteria are isolated from the same soil and water environments as are amoebae, and experimental models using Acanthamoeba spp. and Dictyostelium discoideum were exploited to analyse the mechanisms for intracellular survival. Most of these mechanisms have been further reproduced in macrophages for mycobacteria regarded as opportunistic and obligate pathogens. Amoebal cysts may protect intracellular mycobacteria against adverse conditions and may act as a vector for mycobacteria. The latter hypothesis warrants further environmental and clinical studies to better assess the role of free-living amoebae in the epidemiology of infections caused by mycobacteria.
引用
收藏
页码:894 / 905
页数:12
相关论文
共 117 条
[1]   Survival and growth of Francisella tularensis in Acanthamoeba castellanii [J].
Abd, H ;
Johansson, T ;
Golovliov, I ;
Sandström, G ;
Forsman, M .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2003, 69 (01) :600-606
[2]   Type VII secretion - mycobacteria show the way [J].
Abdallah, M. Abdallah ;
Gey Van Pittius, Nicolaas C. ;
Champion, Patricia A. DiGiuseppe ;
Cox, Jeffery ;
Luirink, Joen ;
Vandenbroucke-Grauls, Christina M. J. E. ;
Appelmelk, Ben J. ;
Bitter, Wilbert .
NATURE REVIEWS MICROBIOLOGY, 2007, 5 (11) :883-891
[3]   Amoebal coculture of "Mycobacterium massiliense" sp nov from the sputum of a patient with hemoptoic pneumonia [J].
Adékambi, T ;
Gaubert, MR ;
Greub, G ;
Gevaudan, MJ ;
La Scola, B ;
Raoult, D ;
Drancourt, M .
JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (12) :5493-5501
[4]   Survival of environmental mycobacteria in Acanthamoeba polyphaga [J].
Adekambi, Toidi ;
Ben Salah, Skandar ;
Khlif, Mohamed ;
Raoult, Didier ;
Drancourt, Michel .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2006, 72 (09) :5974-5981
[5]   Molecular Analysis of a Leprosy Immunotherapeutic Bacillus Provides Insights into Mycobacterium Evolution [J].
Ahmed, Niyaz ;
Saini, Vikram ;
Raghuvanshi, Saurabh ;
Khurana, Jitendra P. ;
Tyagi, Akhilesh K. ;
Tyagi, Anil K. ;
Hasnain, Seyed E. .
PLOS ONE, 2007, 2 (10)
[6]  
Aksozek A, 2002, J PARASITOL, V88, P621, DOI 10.1645/0022-3395(2002)088[0621:ROACCT]2.0.CO
[7]  
2
[8]   PHAGOCYTOSIS IN ACANTHAMOEBA .1. A MANNOSE RECEPTOR IS RESPONSIBLE FOR THE BINDING AND PHAGOCYTOSIS OF YEAST [J].
ALLEN, PG ;
DAWIDOWICZ, EA .
JOURNAL OF CELLULAR PHYSIOLOGY, 1990, 145 (03) :508-513
[9]   Molecular identification of potential pathogens in water and air of a hospital therapy pool [J].
Angenent, LT ;
Kelley, ST ;
St Amand, A ;
Pace, NR ;
Hernandez, MT .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2005, 102 (13) :4860-4865
[10]   Differential trafficking of live and dead Mycobacterium marinum organisms in macrophages [J].
Barker, LP ;
George, KM ;
Falkow, S ;
Small, PLC .
INFECTION AND IMMUNITY, 1997, 65 (04) :1497-1504